8GEQ
E. eligens beta-glucuronidase bound to ceritinib-glucuronide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-glucuronidase | polymer | 614 | 69835.1 | 1 | UniProt (A0A174ZZA3) Pfam (PF02837) Pfam (PF00703) Pfam (PF02836) In PDB | Lachnospira eligens | |
| 2 | A | 4-amino-5-chloro-2-{4-(1-beta-D-glucopyranuronosylpiperidin-4-yl)-5-methyl-2-[(propan-2-yl)oxy]anilino}pyrimidine | non-polymer | 552.0 | 1 | Chemie (ZFW) | |||
| 3 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 1 - 611 (UniProt: A0A174ZZA3)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Asp 120 | His 120 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 69835.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 552.0 | |
| All* | Total formula weight | 70387.1 |
