PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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1JHL	THREE-DIMENSIONAL STRUCTURE OF A HETEROCLITIC ANTIGEN-ANTIBODY CROSS-REACTION COMPLEX 分子名称: IGG1-KAPPA D11.15 FV (HEAVY CHAIN), IGG1-KAPPA D11.15 FV (LIGHT CHAIN), PHEASANT EGG WHITE LYSOZYME 著者 Chitarra, V, Alzari, P.M, Bentley, G.A, Bhat, T.N, Eisele, J.-L, Poljak, R.J. 登録日 1993-05-04 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex. Proc.Natl.Acad.Sci.USA, 90, 1993
4RFO	Crystal structure of the ADCC-Potent Antibody N60-I3 Fab in complex with HIV-1 Clade A/E gp120 and M48u1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade A/E gp120, N60-i3 Fab heavy chain, ... 著者 Tolbert, W.D, Gohain, N, Pazgier, M. 登録日 2014-09-26 公開日 2015-07-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
3EO0	Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008 分子名称: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, GLYCEROL 著者 Gruetter, C, Gruetter, M.G. 登録日 2008-09-26 公開日 2008-12-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions Proc.Natl.Acad.Sci.Usa, 105, 2008
7ZQT	Helicobacter pylori adhesin BabA bound to neutralising human antibody. 分子名称: 1,2-ETHANEDIOL, Adhesin binding fucosylated histo-blood group antigen, GLYCEROL, ... 著者 Moonens, K, Boren, T. 登録日 2022-05-03 公開日 2023-05-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Helicobacter pylori adhesin BabA bound to neutralising human antibody. To Be Published
2W9D	Structure of Fab fragment of the ICSM 18 - anti-Prp therapeutic antibody at 1.57 A resolution. 分子名称: CALCIUM ION, ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN 著者 Antonyuk, S.V, Trevitt, C.R, Strange, R.W, Jackson, G.S, Sangar, D, Batchelor, M, Jones, S, Georgiou, T, Cooper, S, Fraser, C, Khalili-Shirazi, A, Clarke, A.R, Hasnain, S.S, Collinge, J. 登録日 2009-01-23 公開日 2009-02-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody. Proc.Natl.Acad.Sci.USA, 106, 2009
2UYL	Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1 分子名称: MONOCLONAL ANTIBODY F-22-30 著者 Ahmed, F, Haouz, A, Nato, F, Fournier, J.M, Alzari, P.M. 登録日 2007-04-10 公開日 2008-05-13 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of a Monoclonal Antibody Directed Against an Antigenic Determinant Common to Ogawa and Inaba Serotypes of Vibrio Cholerae O1. Proteins, 70, 2008
8I5L	Crystal structure of P domain from norovirus GI.4 capsid protein in complex with broad specificity antibody single-chain Fv fragment CV-2F5. 分子名称: Capsid protein, scFv fragment 著者 Kato-Murayama, M, Murayama, K, Shirouzu, M. 登録日 2023-01-26 公開日 2024-01-31 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies. J.Virol., 98, 2024
6P95	Structure of Lassa virus glycoprotein in complex with Fab 25.6A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Saphire, E.O, Hastie, K.M. 登録日 2019-06-09 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization. Cell, 178, 2019
5V2A	Crystal structure of Fab H7.167 in complex with influenza virus hemagglutinin from A/Shanghai/02/2013 (H7N9) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H7.167 antibody, Hemagglutinin, ... 著者 Zhang, H, Zhu, X, Wilson, I.A. 登録日 2017-03-03 公開日 2017-04-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.656 Å) 主引用文献 H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. J. Clin. Invest., 126, 2016
8IPC	The recombinant NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 181 and 184 分子名称: Putative zinc metalloprotease aq_1964, The recombinantly-expressed heavy chain of the monoclonal antibody NZ-1, The recombinantly-expressed light chain of the monoclonal antibody NZ-1 著者 Adachi, Y, Nogi, T. 登録日 2023-03-14 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recombinant production of antibody antigen-binding fragments with an N-terminal human growth hormone tag in mammalian cells. Protein Expr.Purif., 208-209, 2023
8VY4	Engineering a Tumor-Selective Prodrug T Cell Engager Bispecific Antibody for Safer Immunotherapy 分子名称: Fab Heavy Chain, Fab Light Chain, PCA-ASP-GLY-ASN-GLU-GLU-MET 著者 Antonysamy, S, Demarest, S, Froning, K, Hickey, M.H, Kuhlman, B, McCue, A.C. 登録日 2024-02-06 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy. Mabs, 16, 2024
6CRK	Heterotrimeric G-protein in complex with an antibody fragment 分子名称: CITRATE ANION, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Maeda, S, Dawson, R, Kobilka, B. 登録日 2018-03-19 公開日 2018-10-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Development of an antibody fragment that stabilizes GPCR/G-protein complexes. Nat Commun, 9, 2018
6IDL	Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class II particle) 分子名称: Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... 著者 Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. 登録日 2018-09-10 公開日 2018-12-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (25 Å) 主引用文献 Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
6PDR	Vaccine-elicited murine FP-targeting antibody vFP25.18 in complex with HIV fusion peptide (residue 512-519) 分子名称: HIV fusion peptide residue 512-519, antibody vFP25.18 heavy chain, antibody vFP25.18 light chain 著者 Xu, K, Liu, K, Wang, Y, Kwong, P.D. 登録日 2019-06-19 公開日 2020-06-24 実験手法 X-RAY DIFFRACTION (1.555 Å) 主引用文献 Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies To Be Published
6PDU	Vaccine-elicited NHP FP-targeting antibody 13N024-a.01 in complex with HIV fusion peptide (residue 512-519) 分子名称: HIV-1 fusion peptide residue 512-519, antibody 13N024-a.01, heavy chain, ... 著者 Xu, K, Liu, K, Wang, Y, Kwong, P.D. 登録日 2019-06-19 公開日 2020-06-24 実験手法 X-RAY DIFFRACTION (1.953 Å) 主引用文献 Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies To Be Published
1A3L	CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION 分子名称: 1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE, IMMUNOGLOBULIN FAB 13G5 (HEAVY CHAIN), IMMUNOGLOBULIN FAB 13G5 (LIGHT CHAIN) 著者 Heine, A, Wilson, I.A. 登録日 1998-01-22 公開日 1999-02-16 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution. Science, 279, 1998
5D6C	Structure of 4497 Fab bound to synthetic wall teichoic acid fragment 分子名称: 4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-5-O-phosphono-D-ribitol, 4497 antibody IgG1 (VH and CH1), 4497 antibody IgK (VL and CL), ... 著者 Lupardus, P.J, Fong, R. 登録日 2015-08-12 公開日 2015-11-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Novel antibody-antibiotic conjugate eliminates intracellular S. aureus. Nature, 527, 2015
6J5G	Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein 分子名称: Envelope protein E, antibody heavy chain, antibody light chain 著者 Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. 登録日 2019-01-10 公開日 2019-02-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.291 Å) 主引用文献 Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
6J5D	Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III 分子名称: Envelope, antibody heavy chain, antibody light chain 著者 Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. 登録日 2019-01-10 公開日 2019-02-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
6J5F	Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein Domain III 分子名称: Envelope protein, antibody heavy chain, antibody light chain 著者 Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. 登録日 2019-01-10 公開日 2019-02-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
5D8I	Engineering the Species-Specificity of an Inhibitory Antibody Targeting a Modulator of Tumor Stroma 分子名称: Sulfhydryl oxidase 1 著者 Grossman, I, Fass, D. 登録日 2015-08-17 公開日 2016-02-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma. Protein Eng.Des.Sel., 29, 2016
4RIS	Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk 分子名称: CH58-UA Fab heavy chain, CH58-UA Fab light chain, Envelope glycoprotein 著者 Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. 登録日 2014-10-07 公開日 2015-08-12 最終更新日 2015-09-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015
4RIR	Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk 分子名称: CH58-UA Fab heavy chain, CH58-UA Fab light chain 著者 Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. 登録日 2014-10-07 公開日 2015-08-12 最終更新日 2015-09-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015
6CMG	Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-Reactive Neutralizing Human Monoclonal Antibody m102.3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G, ... 著者 Xu, K, Nikolov, D. 登録日 2018-03-05 公開日 2018-04-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody. PLoS Pathog., 9, 2013
6IVZ	Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state 分子名称: Envelope protein, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A 著者 Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. 登録日 2018-12-04 公開日 2019-02-13 最終更新日 2019-02-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019

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