5XB5
 
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5XAI
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1EFL
 | | HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE | | 分子名称: | MAGNESIUM ION, MALIC ENZYME, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Yang, Z, Floyd, D.L, Loeber, G, Tong, L. | | 登録日 | 2000-02-09 | | 公開日 | 2000-03-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
Nat.Struct.Biol., 7, 2000
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6KHA
 | | Solution structure of bovine insulin amyloid intermediate-2 | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A. | | 登録日 | 2019-07-14 | | 公開日 | 2020-08-12 | | 最終更新日 | 2020-11-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
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6BOJ
 | | Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with BPN5004 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(4-{[2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl]methyl}phenyl)acetamide, CHLORIDE ION, ... | | 著者 | Fox III, D, Fairman, J.W, Gurney, M.E. | | 登録日 | 2017-11-20 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice.
Neuropsychopharmacology, 43, 2018
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1PNF
 | | PNGASE F COMPLEX WITH DI-N-ACETYLCHITOBIOSE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F, SULFATE ION | | 著者 | Van Roey, P, Kuhn, P. | | 登録日 | 1995-10-11 | | 公開日 | 1996-03-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Active site and oligosaccharide recognition residues of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F.
J.Biol.Chem., 270, 1995
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5XB2
 | | ADP-Mg-F-dTMP bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Biswas, A, Jeyakanthan, J, Sekar, K. | | 登録日 | 2017-03-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.161 Å) | | 主引用文献 | Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate
FEBS J., 284, 2017
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6MGN
 | | mouse Id1 (51-104) - human hE47 (348-399) complex | | 分子名称: | DNA-binding protein inhibitor ID-1, Transcription factor E2-alpha | | 著者 | Benezra, R, Pavletich, N.P, Gall, A.-L, Goldgur, Y. | | 登録日 | 2018-09-14 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
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6MID
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6MGM
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6MGQ
 | | ERAP1 in the open conformation bound to 10mer phosphinic inhibitor DG014 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 1, Phosphinic inhibitor DG014, ... | | 著者 | Stern, L.J, Maben, Z. | | 登録日 | 2018-09-14 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism.
Nat Commun, 12, 2021
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6BBD
 | | Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | van Eijk, M, Rynkiewicz, M.J, Khatri, K, Leymarie, N, Zaia, J, White, M.R, Hartshorn, K.L, Cafarella, T.R, van Die, I, Hessing, M, Seaton, B.A, Haagsman, H.P. | | 登録日 | 2017-10-18 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus.
J. Biol. Chem., 293, 2018
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1YR8
 | | PAB0955 crystal structure : a GTPase in GTP bound form from Pyrococcus abyssi | | 分子名称: | ATP(GTP)binding protein, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | | 登録日 | 2005-02-03 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family.
Embo Rep., 8, 2007
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6C95
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6C9M
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1BX6
 | | CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE | | 分子名称: | BALANOL, CAMP-DEPENDENT PROTEIN KINASE | | 著者 | Narayana, N, Xuong, N.-H, Ten Eyck, L.F, Taylor, S.S. | | 登録日 | 1998-10-13 | | 公開日 | 1999-04-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.
Biochemistry, 38, 1999
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1LFV
 | | OXY HEMOGLOBIN (88% RELATIVE HUMIDITY) | | 分子名称: | Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Biswal, B.K, Vijayan, M. | | 登録日 | 2002-04-12 | | 公開日 | 2002-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of human oxy- and deoxyhaemoglobin at different levels of humidity: variability in the T state.
Acta Crystallogr.,Sect.D, 58, 2002
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6MGD
 | | Thermosulfurimonas dismutans KpsC, beta Kdo 2,7 transferase | | 分子名称: | Capsular polysaccharide export system protein KpsC | | 著者 | Doyle, L, Mallette, E, Kimber, M.S, Whitfield, C. | | 登録日 | 2018-09-13 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules.
Nat.Chem.Biol., 15, 2019
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6MQC
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5U34
 | | Crystal structure of AacC2c1-sgRNA binary complex | | 分子名称: | CRISPR-associated endonuclease C2c1, sgRNA | | 著者 | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | | 登録日 | 2016-12-01 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.255 Å) | | 主引用文献 | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
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1XKP
 | | Crystal structure of the virulence factor YopN in complex with its heterodimeric chaperone SycN-YscB | | 分子名称: | Chaperone protein sycN, Chaperone protein yscB, putative membrane-bound Yop targeting protein YopN | | 著者 | Schubot, F.D, Jackson, M.W, Penrose, K.J, Cherry, S, Tropea, J.E, Plano, G.V, Waugh, D.S. | | 登録日 | 2004-09-29 | | 公開日 | 2005-03-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis.
J.Mol.Biol., 346, 2005
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1IVI
 | | Crystal Structure of pig dihydrolipoamide dehydrogenase | | 分子名称: | dihydrolipoamide dehydrogenase | | 著者 | Toyoda, T, Kobayashi, R, Sekiguchi, T, Koike, K, Koike, M, Takenaka, A. | | 登録日 | 2002-03-15 | | 公開日 | 2003-03-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (8 Å) | | 主引用文献 | Crystallization and preliminary X-ray analysis of pig E3, lipoamide dehydrogenase.
Acta Crystallogr.,Sect.D, 54, 1998
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6MQM
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1LFL
 | | DEOXY HEMOGLOBIN (90% RELATIVE HUMIDITY) | | 分子名称: | Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Biswal, B.K, Vijayan, M. | | 登録日 | 2002-04-11 | | 公開日 | 2002-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structures of human oxy- and deoxyhaemoglobin at different levels of humidity: variability in the T state.
Acta Crystallogr.,Sect.D, 58, 2002
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6MQR
 | | Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519) | | 分子名称: | CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ... | | 著者 | Xu, K, Wang, Y, Kwong, P.D. | | 登録日 | 2018-10-10 | | 公開日 | 2019-07-31 | | 最終更新日 | 2019-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
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