Crystal structure of R90A mutant of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 5XB5

Related5XAI 5XB2 5XB3 5XBH
DescriptorThymidylate kinase, PHOSPHATE ION (3 entities in total)
Functional Keywordskinase, complex, nucleotide binding, transferase
Biological sourceAquifex aeolicus (strain VF5)
Total number of polymer chains2
Total molecular weight44823.63
Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2017-03-15, release date: 2017-06-28, Last modification date: 2017-08-30)
Primary citation
Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K.
Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate.
FEBS J., 284:2527-2544, 2017
PubMed: 28627020 (PDB entries with the same primary citation)
DOI: 10.1111/febs.14140
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28720.5%2.3%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-12