PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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3L32	Structure of the dimerisation domain of the rabies virus phosphoprotein 分子名称: Phosphoprotein 著者 Ivanov, I, Crepin, T, Jamin, M, Ruigrok, R.W.H. 登録日 2009-12-16 公開日 2010-02-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the dimerisation domain of the rabies virus phosphoprotein J.Virol., 2010
4YWD	Structure of rat cytosolic pepck in complex with 2,3-Pyridine dicarboxylic acid 分子名称: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... 著者 Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. 登録日 2015-03-20 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
5QSC	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z300245038 分子名称: N-[(3-fluorophenyl)methyl]-N-methylsulfuric diamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 PanDDA analysis group deposition To Be Published
4O1Y	Crystal structure of Porcine Pancreatic Phospholipase A2 in complex with 1-Naphthaleneacetic acid 分子名称: CALCIUM ION, NAPHTHALEN-1-YL-ACETIC ACID, Phospholipase A2, ... 著者 Dileep, K.V, Remya, C, Tintu, I, Mandal, P.K, Karthe, P, Haridas, M, Sadasivan, C. 登録日 2013-12-16 公開日 2014-01-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Porcine Pancreatic Phospholipase A2 in complex with 1-Naphthaleneacetic acid To be published
4FJ3	14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide 分子名称: 14-3-3 protein zeta/delta, RAF proto-oncogene serine/threonine-protein kinase 著者 Ottmann, C, Molzan, M. 登録日 2012-06-11 公開日 2012-09-05 最終更新日 2013-07-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer J.Mol.Biol., 423, 2012
4WUL	Crystal structure of E. faecalis DNA binding domain LiaRD191N complexed with 26bp DNA 分子名称: DNA (26-MER), Response regulator receiver domain protein 著者 Davlieva, M, Shamoo, Y. 登録日 2014-11-02 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin. Nucleic Acids Res., 43, 2015
5QSE	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2017168803 分子名称: (2S)-2-[(3-fluoropyridin-2-yl)(methyl)amino]propan-1-ol, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 PanDDA analysis group deposition To Be Published
7T5Q	Cryo-EM Structure of a Transition State of Arp2/3 Complex Activation 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Rebowski, G, van Eeuwen, T, Boczkowska, M, Dominguez, R. 登録日 2021-12-13 公開日 2023-06-14 最終更新日 2023-08-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ) To Be Published
5QSF	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434814 分子名称: 3-(diethylamino)phenol, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 PanDDA analysis group deposition To Be Published
6POR	Antimicrobial lasso peptide ubonodin 分子名称: Ubonodin 著者 Link, A.J, Cheung-Lee, W.L. 登録日 2019-07-05 公開日 2019-12-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem, 21, 2020
5NBL	Crystal structure of the Arp4-N-actin(APO-state) heterodimer bound by a nanobody 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... 著者 Knoll, K.R, Eustermann, S, Hopfner, K.P. 登録日 2017-03-02 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling. Nat. Struct. Mol. Biol., 25, 2018
5LUX	Homeobox transcription factor CDX1 bound to methylated DNA 分子名称: DNA (5'-D(P*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*C)-3'), ... 著者 Morgunova, E, Popov, A, Taipale, J. 登録日 2016-09-12 公開日 2017-05-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
4P2P	AN INDEPENDENT CRYSTALLOGRAPHIC REFINEMENT OF PORCINE PHOSPHOLIPASE A2 AT 2.4 ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, PHOSPHOLIPASE A2 著者 Finzel, B.C, Ohlendorf, D.H, Weber, P.C, Salemme, F.R. 登録日 1991-10-22 公開日 1992-01-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An independent crystallographic refinement of porcine phospholipase A2 at 2.4 A resolution Acta Crystallogr.,Sect.B, 47, 1991
5LTW	Complex of human 14-3-3 sigma CLU1 mutant with phosphorylated heat shock protein B6 分子名称: 14-3-3 protein sigma, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heat shock protein beta-6, ... 著者 Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V. 登録日 2016-09-07 公開日 2017-02-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator. Structure, 25, 2017
5DC7	Crystal structure of D176A-Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: Fluor-de-Lys tetrapeptide assay substrate, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Lee, M.S, Christianson, D.W. 登録日 2015-08-23 公開日 2016-02-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
6PTL	Structure of the self-association domain of the chromatin looping factor LDB1 分子名称: LIM domain-binding protein 1 著者 Macindoe, I, Silva, A, Guss, J.M, Mackay, J.P, Matthews, J.M. 登録日 2019-07-16 公開日 2020-07-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the self-association domain of the chromatin looping factor LDB1 To Be Published
5OO0	Cdk2(WT) covalent adduct with D28 at C177 分子名称: Cyclin-dependent kinase 2, methyl 4-propanoyl-2,3-dihydroquinoxaline-1-carboxylate 著者 Craven, G, Morgan, R.M.L, Mann, D.J. 登録日 2017-08-04 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery. Angew. Chem. Int. Ed. Engl., 57, 2018
5NBN	Crystal structure of the Arp4-N-actin-Arp8-Ino80HSA module of INO80 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-like protein ARP8, ... 著者 Knoll, K.R, Eustermann, S, Hopfner, K.P. 登録日 2017-03-02 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling. Nat. Struct. Mol. Biol., 25, 2018
5NEV	CDK2/Cyclin A in complex with compound 73 分子名称: 4-[[6-(3-phenylphenyl)-7~{H}-purin-2-yl]amino]benzenesulfonamide, Cyclin-A2, Cyclin-dependent kinase 2 著者 Coxon, C.R, Anscombe, E, Harnor, S.J, Martin, M.P, Carbain, B, Hardcastle, I.R, Harlow, L.K, Korolchuk, S, Matheson, C.J, Noble, M.E.M, Newell, D.R, Turner, D, Sivaprakasam, M, Wang, L.Z, Wong, C, Golding, B.T, Griffin, R.J, Cano, G. 登録日 2017-03-12 公開日 2017-03-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J. Med. Chem., 60, 2017
4QTB	Structure of human ERK1 in complex with SCH772984 revealing a novel inhibitor-induced binding pocket 分子名称: (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Chaikuad, A, Keates, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2014-07-07 公開日 2014-07-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics. Nat.Chem.Biol., 10, 2014
5U8S	Structure of eukaryotic CMG helicase at a replication fork 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (26-MER), ... 著者 Li, H, Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, O'Donnell, M.E. 登録日 2016-12-14 公開日 2017-01-25 最終更新日 2020-01-01 実験手法 ELECTRON MICROSCOPY (6.101 Å) 主引用文献 Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ABW	Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases 分子名称: 1-(3-CHLOROPHENYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-6-METHYL-N-[4-(METHYLSULFONYL)BENZYL]-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 von Nussbaum, F, Li, V.M, Schaefer, M. 登録日 2015-08-10 公開日 2015-08-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases: Into clinical testing with pre-adaptive pharmacophores. Bioorg. Med. Chem. Lett., 25, 2015
4WU4	Crystal structure of E. faecalis DNA binding domain LiaRD191N complexed with 22bp DNA 分子名称: DNA (5'-D(P*AP*AP*AP*TP*CP*GP*TP*TP*CP*TP*TP*AP*AP*GP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*CP*TP*TP*AP*AP*GP*AP*AP*CP*GP*AP*TP*TP*T)-3'), GLYCEROL, ... 著者 Davlieva, M, Shamoo, Y. 登録日 2014-10-31 公開日 2015-05-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin. Nucleic Acids Res., 43, 2015
5D1J	CRYSTAL STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2-WT) COMPLEX WITH N-[5-[[[5-(1,1-DIMETHYLETHYL)-2-OXAZOLYL] METHYL]THIO]-2-THIAZOLYL]-4-PIPERIDINECARBOXAMIDE (BMS-387032) 分子名称: Cyclin-dependent kinase 2, N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide 著者 Sack, J.S. 登録日 2015-08-04 公開日 2015-08-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 N-(Cycloalkylamino)Acyl-2-Aminothiazole Inhibitors Of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl) -2-Oxazolyl]Methyl]Thio]-2-Thiazolyl]-4-Piperidinecarboxamide (Bms-387032), A Highly Efficacious And Selective Antitumor Agent J.Med.Chem., 47, 2004
4WVP	Crystal structure of an activity-based probe HNE complex 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BTN-3V3-NLB-OMT-OIC-3V2, ... 著者 Lechtenberg, B.C, Kasperkiewicz, P, Robinson, H.R, Drag, M, Riedl, S.J. 登録日 2014-11-06 公開日 2015-02-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 The Elastase-PK101 Structure: Mechanism of an Ultrasensitive Activity-based Probe Revealed. Acs Chem.Biol., 10, 2015

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