5QSE

PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2017168803

Summary for 5QSE

• Entry DOI: 10.2210/pdb5qse/pdb
• Group deposition: PanDDA analysis group deposition (G_1002081)
• Descriptor: T-box transcription factor T, (2S)-2-[(3-fluoropyridin-2-yl)(methyl)amino]propan-1-ol (3 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 19839.83

Authors

Newman, J.A.,Gavard, A.E.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2019-05-25, release date: 2019-08-21, Last modification date: 2024-03-06)

• Primary citation: Newman, J.A.,Gavard, A.E.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.; PanDDA analysis group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.01 Å)