PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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7QJL	Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: ACETATE ION, BROMIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Levy, C, Katariya, M. 登録日 2021-12-16 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
4O5Q	Crystal Structure of the Alkylhydroperoxide Reductase AhpF from Escherichia coli 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkyl hydroperoxide reductase subunit F, CADMIUM ION, ... 著者 Dip, P.V, Kamariah, N, Manimekalai, M.S.S, Balakrishna, A.M, Gruber, G. 登録日 2013-12-20 公開日 2014-11-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli Acta Crystallogr.,Sect.D, 70, 2014
6QLF	Structure of inner kinetochore CCAN complex with mask1 分子名称: Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ... 著者 Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. 登録日 2019-01-31 公開日 2019-10-02 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574, 2019
6Q4D	CDK2 in complex with FragLite31 分子名称: 2-(4-bromanyl-2-methoxy-phenyl)ethanoic acid, Cyclin-dependent kinase 2 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
4O63	Co-enzyme Induced Conformational Changes in Bovine Eye Glyceraldehyde 3-Phosphate Dehydrogenase 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Baker, B.Y, Shi, W, Wang, B, Palczewski, K. 登録日 2013-12-20 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. Protein Sci., 23, 2014
6Q52	Structure of a psychrophilic CCA-adding enzyme in complex with CMPcPP at room temperature in ChipX microfluidic device 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, CCA-adding enzyme 著者 de Wijn, R, Hennig, O, Rollet, K, Bluhm, A, Betat, H, Moerl, M, Lorber, B, Sauter, C. 登録日 2018-12-06 公開日 2019-05-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography. Iucrj, 6, 2019
7LTE	Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA) heteromeric complex (with SAH) 分子名称: LigA domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, TP-methylase family protein 著者 Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. 登録日 2021-02-19 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
7QLS	CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NADH, AND DIMETHOXYPHENYL ACETAMIDE 分子名称: 2-(3,4-dimethoxyphenyl)ethanamide, ADENOSINE-5-DIPHOSPHORIBOSE, FE (III) ION, ... 著者 Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M. 登録日 2021-12-20 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity. Iucrj, 10, 2023
7LTC	Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA) heteromeric complex (no cofactor) 分子名称: LigA domain-containing protein, TP-methylase family protein 著者 Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. 登録日 2021-02-19 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
1MO6	RECA-DATP-MG COMPLEX 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, RecA 著者 Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC) 登録日 2002-09-07 公開日 2003-02-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition Proteins, 50, 2003
3UDO	Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni 分子名称: 1,2-ETHANEDIOL, 3-isopropylmalate dehydrogenase, SULFATE ION 著者 Tkaczuk, K.L, Chruszcz, M, Blus, B.J, Onopriyenko, O, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-10-28 公開日 2011-11-09 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni To be Published
7QNH	CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NADH, AND GLYCEROL 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE (III) ION, GLYCEROL, ... 著者 Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M. 登録日 2021-12-20 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity. Iucrj, 10, 2023
7LTF	Structure of the alpha-N-methyltransferase (SonM mutant Y58F) and RiPP precursor (SonA) heteromeric complex (no cofactor) 分子名称: LigA domain-containing protein, TP-methylase family protein 著者 Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. 登録日 2021-02-19 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
6QC9	Ovine respiratory complex I FRC open class 4 分子名称: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Letts, J.A, Sazanov, L.A. 登録日 2018-12-27 公開日 2019-08-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk. Mol.Cell, 75, 2019
7LX6	T4 lysozyme mutant L99A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(2-phenylethyl)sulfanyl]-1H-1,2,3-triazole, Lysozyme 著者 Kamenik, A.S, Singh, I, Lak, P, Balius, T.E, Liedl, K.R, Shoichet, B.K. 登録日 2021-03-03 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Energy penalties enhance flexible receptor docking in a model cavity. Proc.Natl.Acad.Sci.USA, 118, 2021
7LTR	Structure of the heteromeric complex between the alpha-N-methyltransferase (SonM) and a truncated construct of the RiPP precursor (SonA) (with SAM) 分子名称: GLYCEROL, LigA domain-containing protein, S-ADENOSYLMETHIONINE, ... 著者 Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. 登録日 2021-02-19 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
7QKE	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with inhibitor (surface entropy reduction mutant) 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase, ethyl 1-(cyclohexylmethyl)-5-pyridin-4-yl-indole-2-carboxylate 著者 Snee, M, Tunnicliffe, R, Leys, D, Levy, C, Katariya, M. 登録日 2021-12-17 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
6QDT	Crystal structure of 14-3-3sigma in complex with a RapGef2 pT740 phosphopeptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C. 登録日 2019-01-02 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth. Cell Chem Biol, 27, 2020
4O55	HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid 分子名称: (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION 著者 Feng, L, Kvaratskhelia, M. 登録日 2013-12-19 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase. Plos Pathog., 10, 2014
7LTH	Structure of the alpha-N-methyltransferase (SonM mutant Y93F) and RiPP precursor (SonA) heteromeric complex (no cofactor) 分子名称: LigA domain-containing protein, TP-methylase family protein 著者 Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. 登録日 2021-02-19 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
7QLQ	CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NAD, AND DIMETHOXYPHENYL ACETAMIDE 分子名称: 2-(3,4-dimethoxyphenyl)ethanamide, ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, ... 著者 Sridhar, S, Kiema, T.R, Widersten, M, Wierenga, R.K. 登録日 2021-12-20 公開日 2022-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity. Iucrj, 10, 2023
7LTS	Structure of the alpha-N-methyltransferase (SonM mutant R67A) and RiPP precursor (SonA) heteromeric complex (with SAH) 分子名称: LigA domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, TP-methylase family protein 著者 Miller, F.S, Crone, K.K, Jensen, M.R, Shaw, S, Harcombe, W.R, Elias, M, Freeman, M.F. 登録日 2021-02-20 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis. Nat Commun, 12, 2021
1LZT	REFINEMENT OF TRICLINIC LYSOZYME 分子名称: HEN EGG WHITE LYSOZYME 著者 Hodsdon, J.M, Brown, G.M, Sieker, L.C, Jensen, L.H. 登録日 1985-04-01 公開日 1985-07-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Refinement of triclinic lysozyme: I. Fourier and least-squares methods. Acta Crystallogr.,Sect.B, 46, 1990
3UF9	Crystal structure of SsoPox in complex with the phosphotriester fensulfothion 分子名称: Aryldialkylphosphatase, COBALT (II) ION, FE (II) ION, ... 著者 Elias, M, Gotthard, G, Hiblot, J, Chabriere, E. 登録日 2011-10-31 公開日 2012-10-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Characterisation of the organophosphate hydrolase catalytic activity of SsoPox Sci Rep, 2, 2012
4O5U	Crystal structure of Alkylhydroperoxide Reductase subunit F from E. coli at 2.65 Ang resolution 分子名称: Alkyl hydroperoxide reductase subunit F, CADMIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Kamariah, N, Dip, P.V, Manimekalai, M.S.S, Gruber, G, Eisenhaber, F, Eisenhaber, B. 登録日 2013-12-20 公開日 2014-11-05 最終更新日 2015-02-25 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli Acta Crystallogr.,Sect.D, 70, 2014

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