2OJI
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1FV5
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![BU of 1fv5 by Molmil](/molmil-images/mine/1fv5) | SOLUTION STRUCTURE OF THE FIRST ZINC FINGER FROM THE DROSOPHILA U-SHAPED TRANSCRIPTION FACTOR | 分子名称: | FIRST ZINC FINGER OF U-SHAPED, ZINC ION | 著者 | Liew, C.K, Kowalski, K, Fox, A.H, Newton, A, Sharpe, B.K, Crossley, M, Mackay, J.P. | 登録日 | 2000-09-18 | 公開日 | 2000-10-04 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions. Structure Fold.Des., 8, 2000
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2OJJ
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8VEW
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![BU of 8vew by Molmil](/molmil-images/mine/8vew) | Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 24 | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5-{2-[(2R,5S)-5-methyl-2-phenylpiperidin-1-yl](oxo)acetamido}pyridine-3-carboxamide, CHLORIDE ION, ... | 著者 | Whittington, D.A. | 登録日 | 2023-12-20 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP -Deleted Cancers. J.Med.Chem., 67, 2024
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8VEO
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![BU of 8veo by Molmil](/molmil-images/mine/8veo) | Crystal structure of PRMT5:MEP50 in complex with MTA | 分子名称: | 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Whittington, D.A. | 登録日 | 2023-12-20 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP -Deleted Cancers. J.Med.Chem., 67, 2024
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5ZHX
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2OJG
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1BX6
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![BU of 1bx6 by Molmil](/molmil-images/mine/1bx6) | CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE | 分子名称: | BALANOL, CAMP-DEPENDENT PROTEIN KINASE | 著者 | Narayana, N, Xuong, N.-H, Ten Eyck, L.F, Taylor, S.S. | 登録日 | 1998-10-13 | 公開日 | 1999-04-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase. Biochemistry, 38, 1999
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1BKX
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![BU of 1bkx by Molmil](/molmil-images/mine/1bkx) | A BINARY COMPLEX OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND ADENOSINE FURTHER DEFINES CONFORMATIONAL FLEXIBILITY | 分子名称: | ADENOSINE MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE | 著者 | Narayana, N, Cox, S, Xuong, N, Ten Eyck, L.F, Taylor, S.S. | 登録日 | 1997-07-01 | 公開日 | 1998-03-18 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility. Structure, 5, 1997
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3UVN
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![BU of 3uvn by Molmil](/molmil-images/mine/3uvn) | Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1A | 分子名称: | Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5 | 著者 | Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. | 登録日 | 2011-11-30 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
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2WZR
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![BU of 2wzr by Molmil](/molmil-images/mine/2wzr) | The Structure of Foot and Mouth Disease Virus Serotype SAT1 | 分子名称: | POLYPROTEIN | 著者 | Adams, P, Lea, S, Newman, J, Blakemore, W, King, A, Stuart, D, Fry, E. | 登録日 | 2009-12-02 | 公開日 | 2010-12-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Structure of Foot-and-Mouth Disease Virus Serotype Sat1. To be Published
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8DY5
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8DY1
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1FU9
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![BU of 1fu9 by Molmil](/molmil-images/mine/1fu9) | SOLUTION STRUCTURE OF THE NINTH ZINC-FINGER DOMAIN OF THE U-SHAPED TRANSCRIPTION FACTOR | 分子名称: | U-SHAPED TRANSCRIPTIONAL COFACTOR, ZINC ION | 著者 | Liew, C.K, Kowalski, K, Fox, A.H, Newton, A, Sharpe, B.K, Crossley, M, Mackay, J.P. | 登録日 | 2000-09-14 | 公開日 | 2000-10-04 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions. Structure Fold.Des., 8, 2000
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3MSX
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![BU of 3msx by Molmil](/molmil-images/mine/3msx) | Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ... | 著者 | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | 登録日 | 2010-04-29 | 公開日 | 2011-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family. To be Published
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5WFC
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1AUI
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![BU of 1aui by Molmil](/molmil-images/mine/1aui) | HUMAN CALCINEURIN HETERODIMER | 分子名称: | CALCIUM ION, FE (III) ION, SERINE/THREONINE PHOSPHATASE 2B, ... | 著者 | Kissinger, C.R, Parge, H.E, Knighton, D.R, Pelletier, L.A, Lewis, C.T, Tempczyk, A, Villafranca, J.E. | 登録日 | 1997-08-27 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature, 378, 1995
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3UR4
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![BU of 3ur4 by Molmil](/molmil-images/mine/3ur4) | Crystal structure of human WD repeat domain 5 with compound | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | 著者 | Dong, A, Dombrovski, L, Senisterra, G, Wernimont, A, Wasney, G.A, Allali Hassani, A, Nguyen, K.T, Smil, D, Bolshan, Y, Hajian, T, Poda, G, Chau, I, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-21 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Biochem. J., 449, 2013
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3UV4
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![BU of 3uv4 by Molmil](/molmil-images/mine/3uv4) | Crystal Structure of the second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1) | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-29 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3UVL
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![BU of 3uvl by Molmil](/molmil-images/mine/3uvl) | Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL3 | 分子名称: | Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5 | 著者 | Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. | 登録日 | 2011-11-30 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
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6IN9
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3QZT
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![BU of 3qzt by Molmil](/molmil-images/mine/3qzt) | Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II | 分子名称: | GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF | 著者 | Li, H, Ruthenburg, A.J, Patel, D.J. | 登録日 | 2011-03-07 | 公開日 | 2011-06-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions. Cell(Cambridge,Mass.), 145, 2011
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3UVM
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![BU of 3uvm by Molmil](/molmil-images/mine/3uvm) | Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL4 | 分子名称: | Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5 | 著者 | Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. | 登録日 | 2011-11-30 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
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1D2N
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![BU of 1d2n by Molmil](/molmil-images/mine/1d2n) | D2 DOMAIN OF N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN | 分子名称: | GLYCEROL, MAGNESIUM ION, N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN, ... | 著者 | Lenzen, C.U, Steinmann, D, Whiteheart, S.W, Weis, W.I. | 登録日 | 1998-06-30 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein. Cell(Cambridge,Mass.), 94, 1998
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3UV5
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![BU of 3uv5 by Molmil](/molmil-images/mine/3uv5) | Crystal Structure of the tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1 | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-29 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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