1AUI

HUMAN CALCINEURIN HETERODIMER

Summary for 1AUI

DescriptorSERINE/THREONINE PHOSPHATASE 2B, ZINC ION, FE (III) ION, ... (6 entities in total)
Functional Keywordshydrolase, phosphatase, immunosuppression
Biological sourceHomo sapiens (human)
Cellular locationNucleus (By similarity) Q08209
Total number of polymer chains2
Total molecular weight78229.95
Authors
Kissinger, C.R.,Parge, H.E.,Knighton, D.R.,Pelletier, L.A.,Lewis, C.T.,Tempczyk, A.,Villafranca, J.E. (deposition date: 1997-08-27, release date: 1997-12-03, Last modification date: 2012-02-29)
Primary citation
Kissinger, C.R.,Parge, H.E.,Knighton, D.R.,Lewis, C.T.,Pelletier, L.A.,Tempczyk, A.,Kalish, V.J.,Tucker, K.D.,Showalter, R.E.,Moomaw, E.W.,Gastinel, L.N.,Habuka, N.,Chen, X.,Maldonado, F.,Barker, J.E.,Bacquet, R.,Villafranca, J.E.
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.
Nature, 378:641-644, 1995
PubMed: 8524402 (PDB entries with the same primary citation)
DOI: 10.1038/378641a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers8 0.2% 4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25