1FV5

SOLUTION STRUCTURE OF THE FIRST ZINC FINGER FROM THE DROSOPHILA U-SHAPED TRANSCRIPTION FACTOR

Summary for 1FV5

• Entry DOI: 10.2210/pdb1fv5/pdb
• Related: 1FU9
• NMR Information: BMRB: 4644
• Descriptor: FIRST ZINC FINGER OF U-SHAPED, ZINC ION (2 entities in total)
• Functional Keywords: zinc finger, cchc, protein interaction, transcription
• Biological source: Drosophila melanogaster (fruit fly)
• Total number of polymer chains: 1
• Total formula weight: 4027.05

Authors

Liew, C.K.,Kowalski, K.,Fox, A.H.,Newton, A.,Sharpe, B.K.,Crossley, M.,Mackay, J.P. (deposition date: 2000-09-18, release date: 2000-10-04, Last modification date: 2024-05-22)

Primary citation

Liew, C.K.,Kowalski, K.,Fox, A.H.,Newton, A.,Sharpe, B.K.,Crossley, M.,Mackay, J.P.
Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions.
Structure Fold.Des., 8:1157-1166, 2000

PubMed Abstract: Zinc finger domains have traditionally been regarded as sequence-specific DNA binding motifs. However, recent evidence indicates that many zinc fingers mediate specific protein-protein interactions. For instance, several zinc fingers from FOG family proteins have been shown to interact with the N-terminal zinc finger of GATA-1.

PubMed: 11080638
DOI: 10.1016/S0969-2126(00)00527-X

Experimental method

SOLUTION NMR