8QV6
 
 | | Structure of human SPNS2 in DDM | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Nanobody D12, Sphingosine-1-phosphate transporter SPNS2 | | 著者 | Li, H.Z, Pike, A.C.W, McKinley, G, Mukhopadhyay, S.M.M, Moreau, C, Scacioc, A, Abrusci, P, Borkowska, O, Chalk, R, Stefanic, S, Burgess-Brown, N, Duerr, K.L, Sauer, D.B. | | 登録日 | 2023-10-17 | | 公開日 | 2025-02-19 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2.
Nat Commun, 16, 2025
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5BZZ
 | | Crystal structure of human phosphatase PTEN in its reduced state | | 分子名称: | L(+)-TARTARIC ACID, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | | 著者 | Lee, C.-U, Bier, D, Hennig, S, Grossmann, T.N. | | 登録日 | 2015-06-11 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.
Angew.Chem.Int.Ed.Engl., 54, 2015
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7UNE
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1LB6
 | | TRAF6-CD40 Complex | | 分子名称: | CD40 antigen, TNF receptor-associated factor 6 | | 著者 | Ye, H, Arron, J.R, Lamothe, B, Cirilli, M, Kobayashi, T, Shevde, N.K, Segal, D, Dzivenu, O, Vologodskaia, M, Yim, M, Du, K, Singh, S, Pike, J.W, Darnay, B.G, Choi, Y, Wu, H. | | 登録日 | 2002-04-02 | | 公開日 | 2002-07-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Distinct molecular mechanism for initiating TRAF6 signalling.
Nature, 418, 2002
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7UNF
 | | CryoEM structure of a mEAK7 bound human V-ATPase complex | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wang, R, Li, X. | | 登録日 | 2022-04-10 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | | 主引用文献 | Molecular basis of mEAK7-mediated human V-ATPase regulation.
Nat Commun, 13, 2022
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7U4T
 | | Human V-ATPase in state 2 with SidK and mEAK-7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ... | | 著者 | Wang, L, Fu, T.M. | | 登録日 | 2022-03-01 | | 公開日 | 2022-08-24 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6O7X
 | | Saccharomyces cerevisiae V-ATPase Stv1-V1VO State 3 | | 分子名称: | Putative protein YPR170W-B, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L. | | 登録日 | 2019-03-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6WC9
 | | Human open state TMEM175 in KCl | | 分子名称: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | | 著者 | Oh, S, Paknejad, N, Hite, R.K. | | 登録日 | 2020-03-30 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
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7U8O
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7U8R
 | | Structure of porcine kidney V-ATPase with SidK, Rotary State 3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, ... | | 著者 | Tan, Y.Z, Keon, K.A. | | 登録日 | 2022-03-09 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
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7U8Q
 | | Structure of porcine kidney V-ATPase with SidK, Rotary State 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, ... | | 著者 | Tan, Y.Z, Keon, K.A. | | 登録日 | 2022-03-09 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
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5B6M
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7U8P
 | | Structure of porcine kidney V-ATPase with SidK, Rotary State 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, ... | | 著者 | Tan, Y.Z, Keon, K.A. | | 登録日 | 2022-03-09 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
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5L94
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5BOL
 | | DNA polymerase beta ternary complex with a templating 5ClC and incoming dGTP analog | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CDO)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... | | 著者 | Freudenthal, B.D, Wilson, S.H. | | 登録日 | 2015-05-27 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5BZ6
 | | Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium uniporter fused with T4 lysozyme | | 分子名称: | Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION | | 著者 | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | | 登録日 | 2015-06-11 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16, 2015
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5BRM
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5VOX
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3SR0
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2RMQ
 | | Solution structure of fully modified 4'-thioDNA with the sequence of d(CGCGAATTCGCG) | | 分子名称: | DNA (5'-D(*(C4S)P*(S4G)P*(C4S)P*(S4G)P*(S4A)P*(S4A)P*(T49)P*(T49)P*(C4S)P*(S4G)P*(C4S)P*(S4G))-3') | | 著者 | Matsugami, A, Ohyama, T, Inada, M, Katahira, M. | | 登録日 | 2007-11-12 | | 公開日 | 2008-04-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Unexpected A-form formation of 4'-thioDNA in solution, revealed by NMR, and the implications as to the mechanism of nuclease resistance
Nucleic Acids Res., 36, 2008
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5BRK
 | | pMob1-Lats1 complex | | 分子名称: | MOB kinase activator 1A, Serine/threonine-protein kinase LATS1, ZINC ION | | 著者 | Ni, L, Luo, X. | | 登録日 | 2015-05-31 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
Genes Dev., 29, 2015
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5BUG
 | | Crystal structure of human phosphatase PTEN oxidized by H2O2 | | 分子名称: | L(+)-TARTARIC ACID, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | | 著者 | Lee, C.-U, Bier, D, Hennig, S, Grossmann, T.N. | | 登録日 | 2015-06-03 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4KN7
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4KN4
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2B4D
 | | SSAT+COA+SP- SP disordered | | 分子名称: | COENZYME A, Diamine acetyltransferase 1 | | 著者 | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2005-09-23 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa, 103, 2006
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