5BRK

pMob1-Lats1 complex

Summary for 5BRK

• Entry DOI: 10.2210/pdb5brk/pdb
• Related: 5BRM
• Descriptor: MOB kinase activator 1A, Serine/threonine-protein kinase LATS1, ZINC ION, ... (4 entities in total)
• Functional Keywords: pmob1, lats1, hippo, transferase-signaling protein complex, transferase/signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 39117.22

Authors

Ni, L.,Luo, X. (deposition date: 2015-05-31, release date: 2015-07-08, Last modification date: 2019-12-25)

• Primary citation: Ni, L.,Zheng, Y.,Hara, M.,Pan, D.,Luo, X.; Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.; Genes Dev., 29:1416-1431, 2015; PubMed: 26108669; DOI: 10.1101/gad.264929.115

Experimental method

X-RAY DIFFRACTION (2.3 Å)