5L94
The 2.25 A crystal structure of CYP109E1 from Bacillus megaterium in complex with testosterone
Summary for 5L94
Entry DOI | 10.2210/pdb5l94/pdb |
Descriptor | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE, ... (4 entities in total) |
Functional Keywords | bacillus, bacterial proteins, binding sites, catalysis, cytochrome p-450 enzyme system, cytochrome p450, hydroxylation, escherichia coli, heme, ligands, molecular structure, oxidation-reduction, oxygen, protein, protein structure, secondary, steroids, substrate specificity, testosterone, oxidoreductase |
Biological source | Bacillus megaterium (strain DSM 319) |
Total number of polymer chains | 2 |
Total formula weight | 97158.39 |
Authors | Jozwik, I.K.,Thunnissen, A.M.W.H. (deposition date: 2016-06-09, release date: 2016-10-05, Last modification date: 2024-01-10) |
Primary citation | Jozwik, I.K.,Kiss, F.M.,Abdulmughni, A.,Brill, E.,Zapp, J.,Pleiss, J.,Bernhardt, R.,Thunnissen, A.W. Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283:4128-4148, 2016 Cited by PubMed: 27686671DOI: 10.1111/febs.13911 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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