5L94

The 2.25 A crystal structure of CYP109E1 from Bacillus megaterium in complex with testosterone

Summary for 5L94

Entry DOI	10.2210/pdb5l94/pdb
Descriptor	Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE, ... (4 entities in total)
Functional Keywords	bacillus, bacterial proteins, binding sites, catalysis, cytochrome p-450 enzyme system, cytochrome p450, hydroxylation, escherichia coli, heme, ligands, molecular structure, oxidation-reduction, oxygen, protein, protein structure, secondary, steroids, substrate specificity, testosterone, oxidoreductase
Biological source	Bacillus megaterium (strain DSM 319)
Total number of polymer chains	2
Total formula weight	97158.39
Authors	Jozwik, I.K.,Thunnissen, A.M.W.H. (deposition date: 2016-06-09, release date: 2016-10-05, Last modification date: 2024-01-10)
Primary citation	Jozwik, I.K.,Kiss, F.M.,Abdulmughni, A.,Brill, E.,Zapp, J.,Pleiss, J.,Bernhardt, R.,Thunnissen, A.W. Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283:4128-4148, 2016 Cited by PubMed: 27686671 DOI: 10.1111/febs.13911 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation