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5BOL

DNA polymerase beta ternary complex with a templating 5ClC and incoming dGTP analog

Summary for 5BOL
Entry DOI10.2210/pdb5bol/pdb
DescriptorDNA (5'-D(*CP*CP*GP*AP*CP*(CDO)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total)
Functional Keywordstransferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight48279.10
Authors
Freudenthal, B.D.,Wilson, S.H. (deposition date: 2015-05-27, release date: 2015-08-19, Last modification date: 2023-09-27)
Primary citationFedeles, B.I.,Freudenthal, B.D.,Yau, E.,Singh, V.,Chang, S.C.,Li, D.,Delaney, J.C.,Wilson, S.H.,Essigmann, J.M.
Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Proc.Natl.Acad.Sci.USA, 112:E4571-E4580, 2015
Cited by
PubMed: 26243878
DOI: 10.1073/pnas.1507709112
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.981 Å)
Structure validation

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