PDB: 494 件ウェブページステータス検索Chemie searchBIRD

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3UL1	Mouse importin alpha: nucleoplasmin cNLS peptide complex 分子名称: Importin subunit alpha-2, Nucleoplasmin 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3TJ3	Structure of importin a5 bound to the N-terminus of Nup50 分子名称: Importin subunit alpha-1, Nuclear pore complex protein Nup50 著者 Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G. 登録日 2011-08-23 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5. J.Biol.Chem., 287, 2012
3UKZ	Mouse importin alpha: mouse CBP80 cNLS complex 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKY	Mouse importin alpha: yeast CBP80 cNLS complex 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
8SUD	JC Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-05-12 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUQ	STL Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-17 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUS	WU Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-17 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUU	MW Polyomavirus LTA bipartite NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T-antigen 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-17 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUT	Merkel Cell Polyomavirus LTA NLSct bound to importin alpha 2 分子名称: Importin subunit alpha-1, PRO-PRO-LYS-PRO-LYS-LYS-ASN-ARG-GLU 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-17 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUR	Merkel Cell Polyomavirus LTA bipartite NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Truncated large T antigen 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-17 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
3UL0	Mouse importin alpha: mouse CBP80Y8D cNLS complex 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
4RXH	Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS 分子名称: Importin subunit alpha, Large T antigen 著者 Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M. 登録日 2014-12-11 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7553 Å) 主引用文献 Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal. Plos One, 10, 2015
8FK3	Adeno-Associated Virus Porcine Origin capsid protein basic regions in complex with Importin-alpha 2 分子名称: Importin subunit alpha-1, VP1 著者 Hoad, M, Forwood, J.K, Roby, J.A. 登録日 2022-12-20 公開日 2023-03-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Characterization of Porcine Adeno-Associated Virus Capsid Protein with Nuclear Trafficking Protein Importin Alpha Reveals a Bipartite Nuclear Localization Signal. Viruses, 15, 2023
3RZ9	Mouse importin alpha-Ku80 NLS peptide complex 分子名称: Importin subunit alpha-2, Ku80 NLS peptide 著者 Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. 登録日 2011-05-11 公開日 2011-08-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. J.Mol.Biol., 412, 2011
5TBK	Crystal structure of human importin a3 bound to RCC1 分子名称: Importin subunit alpha-3, Regulator of chromosome condensation 著者 Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G. 登録日 2016-09-12 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1. Nat Commun, 8, 2017
5V5O	Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha 分子名称: Importin subunit alpha-1, Nucleoprotein 著者 Sankhala, R.S, Lokareddy, R.K, Cingolani, G. 登録日 2017-03-14 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.243 Å) 主引用文献 Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms. Sci Rep, 7, 2017
5V5P	Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha 分子名称: Importin subunit alpha-1, Nucleoprotein 著者 Sankhala, R.S, Lokareddy, R.K, Cingolani, G. 登録日 2017-03-14 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms. Sci Rep, 7, 2017
3W5K	Crystal structure of Snail1 and importin beta complex 分子名称: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1 著者 Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J. 登録日 2013-01-30 公開日 2014-03-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta. Acta Crystallogr.,Sect.D, 70, 2014
4B18	The crystal structure of human Importin alpha 5 with TERT NLS peptide 分子名称: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE 著者 Kim, K.L, Yoo, J.H, Cho, H.S. 登録日 2012-07-08 公開日 2013-09-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation. J.Cell.Sci., 128, 2015
5VQI	Nuclear transport of the Neurospora crassa NIT2 transcription factor is mediated by Importin-alpha 分子名称: Importin subunit alpha, Nuclear localization sequence of NIT2 transcription factor (NIT2-NLS) 著者 Bernardes, N.E, Fontes, M.R.M. 登録日 2017-05-09 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-alpha. Biochem. J., 474, 2017
5W41	Zika MR766 NLS in complex with Importin alpha subunit-1 分子名称: Importin subunit alpha-1, ZIKA MR766 NLS 著者 Jeffress, S, Smith, K.M, Forwood, J.K. 登録日 2017-06-08 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells. ACS Infect Dis, 2019
7LFC	Structure of importin a3 bound to p50 NLS 分子名称: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit 著者 Florio, T.J, Lokareddy, R.K, Cingolani, G. 登録日 2021-01-16 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022
7LF4	Structure of importin a3 bound to the p50- and p65-NLSs 分子名称: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65 著者 Florio, T.J, Lokareddy, R.K, Cingolani, G. 登録日 2021-01-15 公開日 2022-01-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022
7LEU	Structure of importin a2 bound to p65-NLS 分子名称: Importin subunit alpha-1, Transcription factor p65 著者 Florio, T.J, Lokareddy, R.K, Cingolani, G. 登録日 2021-01-15 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022
7LET	Structure of importin a2 bound to the p50- and p65-NLSs 分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65 著者 Florio, T.J, Lokareddy, R.K, Cingolani, G. 登録日 2021-01-15 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022

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