8TUS

WU Polyomavirus LTA NLS bound to importin alpha 2

Summary for 8TUS

• Entry DOI: 10.2210/pdb8tus/pdb
• Descriptor: Importin subunit alpha-1, Large T antigen (2 entities in total)
• Functional Keywords: importin, karyopherin, nuclear, nls, transport protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 57990.49

Authors

Donnelly, C.M.,Cross, E.M.,Forwood, J.K.,Alvisi, G. (deposition date: 2023-08-17, release date: 2024-02-07, Last modification date: 2024-02-14)

• Primary citation: Cross, E.M.,Akbari, N.,Ghassabian, H.,Hoad, M.,Pavan, S.,Ariawan, D.,Donnelly, C.M.,Lavezzo, E.,Petersen, G.F.,Forwood, J.K.,Alvisi, G.; A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.; Protein Sci., 33:e4876-e4876, 2024; PubMed: 38108201; DOI: 10.1002/pro.4876

Experimental method

X-RAY DIFFRACTION (2.6 Å)