3TJ3

Structure of importin a5 bound to the N-terminus of Nup50

Summary for 3TJ3

• Entry DOI: 10.2210/pdb3tj3/pdb
• Related: 2C1T 2JDQ
• Descriptor: Importin subunit alpha-1, Nuclear pore complex protein Nup50 (3 entities in total)
• Functional Keywords: armadillo repeat, nuclear import adaptor, nls-bearing proteins, nucleo-cytoplasmic shuttling, protein transport
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : P52294; Nucleus, nuclear pore complex : Q9UKX7
• Total number of polymer chains: 4
• Total formula weight: 122414.74

Authors

Pumroy, R.,Nardozzi, J.D.,Hart, D.J.,Root, M.J.,Cingolani, G. (deposition date: 2011-08-23, release date: 2011-11-30, Last modification date: 2023-09-13)

• Primary citation: Pumroy, R.A.,Nardozzi, J.D.,Hart, D.J.,Root, M.J.,Cingolani, G.; Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5.; J.Biol.Chem., 287:2022-2031, 2012; PubMed: 22130666; DOI: 10.1074/jbc.M111.315838

Experimental method

X-RAY DIFFRACTION (2.702 Å)