8TUU
MW Polyomavirus LTA bipartite NLS bound to importin alpha 2
Summary for 8TUU
Entry DOI | 10.2210/pdb8tuu/pdb |
Descriptor | Importin subunit alpha-1, Large T-antigen (3 entities in total) |
Functional Keywords | importin, karyopherin, nuclear, nls, transport protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 57946.53 |
Authors | Cross, E.M.,Forwood, J.K.,Alvisi, G. (deposition date: 2023-08-17, release date: 2024-02-07, Last modification date: 2024-02-14) |
Primary citation | Cross, E.M.,Akbari, N.,Ghassabian, H.,Hoad, M.,Pavan, S.,Ariawan, D.,Donnelly, C.M.,Lavezzo, E.,Petersen, G.F.,Forwood, J.K.,Alvisi, G. A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33:e4876-e4876, 2024 Cited by PubMed: 38108201DOI: 10.1002/pro.4876 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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