5TBK
Crystal structure of human importin a3 bound to RCC1
Summary for 5TBK
Entry DOI | 10.2210/pdb5tbk/pdb |
Related | 4PVZ 5T94 |
Descriptor | Importin subunit alpha-3, Regulator of chromosome condensation (2 entities in total) |
Functional Keywords | nuclear import, importin alpha, rcc1 like domain (rld), nls, protein transport - nuclear protein complex, protein transport / nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 16 |
Total formula weight | 823730.69 |
Authors | Sankhala, R.S.,Lokareddy, R.K.,Pumroy, R.A.,Cingolani, G. (deposition date: 2016-09-12, release date: 2017-09-13, Last modification date: 2023-10-04) |
Primary citation | Sankhala, R.S.,Lokareddy, R.K.,Begum, S.,Pumroy, R.A.,Gillilan, R.E.,Cingolani, G. Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1. Nat Commun, 8:979-979, 2017 Cited by PubMed: 29042532DOI: 10.1038/s41467-017-01057-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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