PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

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6P5I	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2020-02-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
6QAJ	Structure of the tripartite motif of KAP1/TRIM28 分子名称: Endolysin,Transcription intermediary factor 1-beta, ZINC ION 著者 Stoll, G.A, Oda, S, Yu, M, Modis, Y. 登録日 2018-12-19 公開日 2019-07-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing. Proc.Natl.Acad.Sci.USA, 116, 2019
7AAV	Human pre-Bact-2 spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-04 公開日 2020-12-09 最終更新日 2020-12-30 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
7X3U	cryo-EM structure of human TRiC-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... 著者 Cong, Y, Liu, C.X. 登録日 2022-03-01 公開日 2023-06-07 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X3J	Cryo-EM structure of human TRiC-tubulin-S2 分子名称: ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... 著者 Cong, Y, Liu, C.X. 登録日 2022-03-01 公開日 2023-06-07 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X6Q	cryo-EM structure of human TRiC-ATP-closed state 分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... 著者 Cong, Y, Liu, C.X. 登録日 2022-03-08 公開日 2023-06-07 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7X7Y	Cryo-EM structure of Human TRiC-ATP-open state 分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... 著者 Cong, Y, Liu, C.X. 登録日 2022-03-10 公開日 2023-06-07 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM. Commun Biol, 6, 2023
7YCX	The structure of INTAC-PEC complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... 著者 Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. 登録日 2022-07-02 公開日 2023-03-15 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
7DN3	Structure of Human RNA Polymerase III elongation complex 分子名称: DNA (5'-D(P*TP*CP*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*TP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase III subunit RPC1, ... 著者 Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. 登録日 2020-12-08 公開日 2021-03-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
4BKX	The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex 分子名称: ACETATE ION, HISTONE DEACETYLASE 1, METASTASIS-ASSOCIATED PROTEIN MTA1, ... 著者 Millard, C.J, Watson, P.J, Celardo, I, Gordiyenko, Y, Cowley, S.M, Robinson, C.V, Fairall, L, Schwabe, J.W.R. 登録日 2013-04-30 公開日 2013-07-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates. Mol.Cell, 51, 2013
8ITY	human RNA polymerase III pre-initiation complex closed DNA 1 分子名称: DNA (82-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... 著者 Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. 登録日 2023-03-23 公開日 2023-06-07 最終更新日 2023-07-12 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
3RZW	Crystal Structure of the Monobody ySMB-9 bound to human SUMO1 分子名称: GLYCEROL, Monobody ySMB-9, Small ubiquitin-related modifier 1 著者 Gilbreth, R.N, Koide, S. 登録日 2011-05-12 公開日 2011-12-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold. J.Mol.Biol., 415, 2012
2VXD	The structure of the C-terminal domain of Nucleophosmin 分子名称: NUCLEOPHOSMIN 著者 Bycroft, M, Grummitt, C.G. 登録日 2008-07-03 公開日 2008-07-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia. J.Biol.Chem., 283, 2008
6QI9	Truncated human R2TP complex, structure 4 (ADP-empty) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-05-15 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.63 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6QI8	Truncated human R2TP complex, structure 3 (ADP-filled) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-04-10 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6ID0	Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6XOG	Structure of SUMO1-ML786519 adduct bound to SAE 分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... 著者 Sintchak, M, Lane, W, Bump, N. 登録日 2020-07-07 公開日 2021-03-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J.Med.Chem., 64, 2021
6XOH	Structure of SUMO1-ML00789344 adduct bound to SAE 分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... 著者 Sintchak, M, Lane, W, Bump, N. 登録日 2020-07-07 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.226 Å) 主引用文献 Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J.Med.Chem., 64, 2021
6XOI	Structure of SUMO1-ML00752641 adduct bound to SAE 分子名称: SULFATE ION, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... 著者 Sintchak, M, Lane, W, Bump, N. 登録日 2020-07-07 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. J.Med.Chem., 64, 2021
1KPS	Structural Basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin conjugating enzyme Ubc9 and RanGAP1 分子名称: Ran-GTPase activating protein 1, SULFATE ION, Ubiquitin-like protein SUMO-1 conjugating enzyme 著者 Bernier-Villamor, V, Sampson, D.A, Matunis, M.J, Lima, C.D. 登録日 2002-01-02 公開日 2002-02-13 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell(Cambridge,Mass.), 108, 2002
6Z2J	The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex 分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ... 著者 Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R. 登録日 2020-05-16 公開日 2020-07-08 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure. Nat Commun, 11, 2020
6ID1	Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6SWA	Mus musculus brain neocortex ribosome 60S bound to Ebp1 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Kraushar, M.L, Sprink, T. 登録日 2019-09-20 公開日 2020-09-30 最終更新日 2021-02-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. Mol.Cell, 81, 2021
7ABI	Human pre-Bact-2 spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2021-02-10 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
7AO9	Structure of the core MTA1/HDAC1/MBD2 NURD deacetylase complex 分子名称: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... 著者 Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. 登録日 2020-10-14 公開日 2020-11-11 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020

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