6QAJ
Structure of the tripartite motif of KAP1/TRIM28
Summary for 6QAJ
Entry DOI | 10.2210/pdb6qaj/pdb |
Descriptor | Endolysin,Transcription intermediary factor 1-beta, ZINC ION (2 entities in total) |
Functional Keywords | transcriptional repressor; epigenetic silencing; histone h3 lysine 9 methylation (h3k9me3); endogenous retrovirus; retrotransposon; transposable element; tripartite motif (trim); sumo; ubiquitin; e3 ligase, nuclear protein |
Biological source | Enterobacteria phage T4 (Bacteriophage T4) More |
Total number of polymer chains | 2 |
Total formula weight | 123466.98 |
Authors | Stoll, G.A.,Oda, S.,Yu, M.,Modis, Y. (deposition date: 2018-12-19, release date: 2019-07-24, Last modification date: 2024-01-24) |
Primary citation | Stoll, G.A.,Oda, S.I.,Chong, Z.S.,Yu, M.,McLaughlin, S.H.,Modis, Y. Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing. Proc.Natl.Acad.Sci.USA, 116:15042-15051, 2019 Cited by PubMed: 31289231DOI: 10.1073/pnas.1901318116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.901 Å) |
Structure validation
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