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3P87
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Structure of human PCNA bound to RNASEH2B PIP box peptide
分子名称: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B
著者Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
登録日2010-10-13
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
3P83
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BU of 3p83 by Molmil
Structure of the PCNA:RNase HII complex from Archaeoglobus fulgidus.
分子名称: DNA polymerase sliding clamp, Ribonuclease HII
著者Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P.
登録日2010-10-13
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献PCNA directs type 2 RNase H activity on DNA replication and repair substrates.
Nucleic Acids Res., 39, 2011
8F5Q
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BU of 8f5q by Molmil
Crystal structure of human PCNA in complex with the PIP box of FBH1
分子名称: F-box DNA helicase 1, Proliferating cell nuclear antigen
著者Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
登録日2022-11-15
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
2IZO
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BU of 2izo by Molmil
Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex
分子名称: DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ...
著者Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H.
登録日2006-07-25
公開日2006-09-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity.
Nucleic Acids Res., 34, 2006
3GPM
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BU of 3gpm by Molmil
Structure of the trimeric form of the E113G PCNA mutant protein
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-03-23
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
2IX2
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BU of 2ix2 by Molmil
Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus
分子名称: DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C
著者Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H.
登録日2006-07-05
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus.
Acta Crystallogr.,Sect.F, 62, 2006
6J0J
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BU of 6j0j by Molmil
Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani with an unexplained density near residues Pro229,Pr0267 and Ala285
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proliferating cell nuclear antigen
著者Iqbal, N, Sharma, S, Singh, T.P.
登録日2018-12-24
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani with an unexplained density near residues Pro229,Pr0267 and Ala285
To Be Published
3HI8
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BU of 3hi8 by Molmil
Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii
分子名称: Proliferating cell nuclear antigen PcnA
著者Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R.
登録日2009-05-19
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment.
Acta Crystallogr.,Sect.D, 65, 2009
5DA7
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BU of 5da7 by Molmil
monomeric PCNA bound to a small protein inhibitor
分子名称: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ...
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-19
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
3IFV
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BU of 3ifv by Molmil
Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen
分子名称: PCNA, SODIUM ION
著者Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A.
登録日2009-07-26
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation
Bmc Struct.Biol., 9, 2009
2IO4
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BU of 2io4 by Molmil
Crystal structure of PCNA12 dimer from Sulfolobus solfataricus.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ...
著者Hlinkova, V, Ling, H.
登録日2006-10-09
公開日2008-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
8GLA
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BU of 8gla by Molmil
Co-crystal structure of caPCNA bound to the AOH1996 derivative, AOH1996-1LE
分子名称: CHLORIDE ION, N-[2-(3-methoxyphenoxy)phenyl]-N~2~-(naphthalene-1-carbonyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
著者Jossart, J, Perry, J.J.
登録日2023-03-21
公開日2023-07-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
8GL9
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BU of 8gl9 by Molmil
Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE
分子名称: CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
著者Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J.
登録日2023-03-21
公開日2023-07-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
8GJ5
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BU of 8gj5 by Molmil
fungal pcna and peptidomimetic
分子名称: Proliferating cell nuclear antigen, THR-ASP-ILE-ARG-ASN-PHE-PHE-HIS-SER
著者Vandborg, B, Bruning, J.B.
登録日2023-03-14
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus.
J Fungi, 9, 2023
8GJF
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BU of 8gjf by Molmil
afupcna bound with peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B, Bruning, J.B.
登録日2023-03-15
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus.
J Fungi, 9, 2023
3JA9
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BU of 3ja9 by Molmil
Structure of native human PCNA
分子名称: Proliferating cell nuclear antigen
著者Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y.
登録日2015-05-19
公開日2015-12-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
6K2M
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BU of 6k2m by Molmil
Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution.
分子名称: ARGININE, Proliferating cell nuclear antigen
著者Viswanathan, V, Iqbal, N, Sharma, S, Singh, T.P.
登録日2019-05-15
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution.
To Be Published
8GCJ
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BU of 8gcj by Molmil
PCNA
分子名称: Proliferating cell nuclear antigen
著者Vandborg, B.C, Bruning, J.B.
登録日2023-03-01
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of apo pcna
To Be Published
5E0T
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BU of 5e0t by Molmil
Human PCNA mutant - S228I
分子名称: Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6653 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0U
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BU of 5e0u by Molmil
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
2IJX
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BU of 2ijx by Molmil
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
分子名称: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A
著者Hlinkova, V, Ling, H.
登録日2006-10-01
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
6KNC
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BU of 6knc by Molmil
PolD-PCNA-DNA (form B)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.3 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
6HVO
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BU of 6hvo by Molmil
Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION
著者Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A.
登録日2018-10-11
公開日2019-01-23
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
5DAI
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BU of 5dai by Molmil
Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide
分子名称: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-20
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
3GPN
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BU of 3gpn by Molmil
Structure of the non-trimeric form of the E113G PCNA mutant protein
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-03-23
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009

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