PDB: 195 件ウェブページステータス検索Chemie searchBIRD

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6QCG	PCNA complex with Cdt1 N-terminal PIP-box peptide 分子名称: DNA replication factor Cdt1, Proliferating cell nuclear antigen 著者 Perrakis, A, von Castelmur, E. 登録日 2018-12-28 公開日 2019-01-23 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
6QH1	The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide 分子名称: Proliferating cell nuclear antigen, S-phase delaying protein 1 著者 Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A. 登録日 2019-01-14 公開日 2020-02-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide To Be Published
5DAI	Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide 分子名称: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION 著者 Ladner, J.E, Altieri, A.S, Kelman, Z. 登録日 2015-08-20 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
5E0V	Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms 分子名称: Flap endonuclease 1, Proliferating cell nuclear antigen 著者 Duffy, C.M, Hilbert, B.J, Kelch, B.A. 登録日 2015-09-29 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.074 Å) 主引用文献 A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
2IO4	Crystal structure of PCNA12 dimer from Sulfolobus solfataricus. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ... 著者 Hlinkova, V, Ling, H. 登録日 2006-10-09 公開日 2008-04-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
5E0T	Human PCNA mutant - S228I 分子名称: Proliferating cell nuclear antigen 著者 Duffy, C.M, Hilbert, B.J, Kelch, B.A. 登録日 2015-09-29 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6653 Å) 主引用文献 A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
8GL9	Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE 分子名称: CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen 著者 Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J. 登録日 2023-03-21 公開日 2023-07-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Small molecule targeting of transcription-replication conflict for selective chemotherapy. Cell Chem Biol, 30, 2023
8GLA	Co-crystal structure of caPCNA bound to the AOH1996 derivative, AOH1996-1LE 分子名称: CHLORIDE ION, N-[2-(3-methoxyphenoxy)phenyl]-N~2~-(naphthalene-1-carbonyl)-L-alpha-glutamine, Proliferating cell nuclear antigen 著者 Jossart, J, Perry, J.J. 登録日 2023-03-21 公開日 2023-07-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.77 Å) 主引用文献 Small molecule targeting of transcription-replication conflict for selective chemotherapy. Cell Chem Biol, 30, 2023
5DA7	monomeric PCNA bound to a small protein inhibitor 分子名称: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... 著者 Ladner, J.E, Altieri, A.S, Kelman, Z. 登録日 2015-08-19 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
8GJ5	fungal pcna and peptidomimetic 分子名称: Proliferating cell nuclear antigen, THR-ASP-ILE-ARG-ASN-PHE-PHE-HIS-SER 著者 Vandborg, B, Bruning, J.B. 登録日 2023-03-14 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus. J Fungi, 9, 2023
8GJF	afupcna bound with peptide mimetic 分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen 著者 Vandborg, B, Bruning, J.B. 登録日 2023-03-15 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus. J Fungi, 9, 2023
8GCJ	PCNA 分子名称: Proliferating cell nuclear antigen 著者 Vandborg, B.C, Bruning, J.B. 登録日 2023-03-01 公開日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal structure of apo pcna To Be Published
3GPN	Structure of the non-trimeric form of the E113G PCNA mutant protein 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-03-23 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
2IJX	Crystal structure of PCNA3 monomer from Sulfolobus solfataricus. 分子名称: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A 著者 Hlinkova, V, Ling, H. 登録日 2006-10-01 公開日 2007-10-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr.,Sect.D, 64, 2008
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... 著者 Ling, H. 登録日 2008-11-26 公開日 2009-01-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009
5E0U	Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms 分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen 著者 Duffy, C.M, Hilbert, B.J, Kelch, B.A. 登録日 2015-09-29 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
2IZO	Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex 分子名称: DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ... 著者 Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H. 登録日 2006-07-25 公開日 2006-09-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity. Nucleic Acids Res., 34, 2006
2IX2	Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus 分子名称: DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C 著者 Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H. 登録日 2006-07-05 公開日 2006-10-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus. Acta Crystallogr.,Sect.F, 62, 2006
3HI8	Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii 分子名称: Proliferating cell nuclear antigen PcnA 著者 Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R. 登録日 2009-05-19 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.202 Å) 主引用文献 Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment. Acta Crystallogr.,Sect.D, 65, 2009
3F1W	Crystal structure of a mutant proliferating cell nuclear antigen that blocks translesion synthesis 分子名称: Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Ramaswamy, S, Washington, M.T. 登録日 2008-10-28 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Structure of a Mutant Form of Proliferating Cell Nuclear Antigen That Blocks Translesion DNA Synthesis. Biochemistry, 47, 2008
3WGW	Structure of PCNA bound to a small molecule inhibitor 分子名称: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION 著者 Hashimoto, H. 登録日 2013-08-12 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
3IFV	Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen 分子名称: PCNA, SODIUM ION 著者 Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A. 登録日 2009-07-26 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation Bmc Struct.Biol., 9, 2009
3VKX	Structure of PCNA 分子名称: 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... 著者 Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. 登録日 2011-11-26 公開日 2012-03-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
2HIK	heterotrimeric PCNA sliding clamp 分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) 著者 Pascal, J.M, Tsodikov, O.V, Ellenberger, T. 登録日 2006-06-29 公開日 2006-11-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
2HII	heterotrimeric PCNA sliding clamp 分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) 著者 Pascal, J.M, Tsodikov, O.V, Ellenberger, T. 登録日 2006-06-29 公開日 2006-11-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006

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