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6D6K
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Structure of polyribonucleotide nucleotidyltransferase from Acinetobacter baumannii
分子名称: Polyribonucleotide nucleotidyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-04-21
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of polyribonucleotide nucleotidyltransferase from Acinetobacter baumannii
to be published
2VUM
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Alpha-amanitin inhibited complete RNA polymerase II elongation complex
分子名称: 5'-D(*AP*AP*AP*CP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *GP*TP*TP*AP*CP*GP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
著者Brueckner, F, Cramer, P.
登録日2008-05-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation.
Nat.Struct.Mol.Biol., 15, 2008
3PO3
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Arrested RNA Polymerase II reactivation intermediate
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DNA non-template strand, ...
著者Cheung, A.C.M, Cramer, P.
登録日2010-11-21
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of RNA polymerase II backtracking, arrest and reactivation.
Nature, 471, 2011
3JAP
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BU of 3jap by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
分子名称: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
著者Llacer, J.L, Hussain, T, Ramakrishnan, V.
登録日2015-06-18
公開日2015-08-12
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3PO2
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Arrested RNA Polymerase II elongation complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Cheung, A.C.M, Cramer, P.
登録日2010-11-21
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of RNA polymerase II backtracking, arrest and reactivation.
Nature, 471, 2011
3J1N
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Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module
分子名称: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ...
著者Asturias, F.J, Imasaki, T.
登録日2012-03-29
公開日2013-03-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (16 Å)
主引用文献Interaction of the mediator head module with RNA polymerase II.
Structure, 20, 2012
3K1F
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BU of 3k1f by Molmil
Crystal structure of RNA Polymerase II in complex with TFIIB
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P.
登録日2009-09-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献RNA polymerase II-TFIIB structure and mechanism of transcription initiation.
Nature, 462, 2009
6EXN
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BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
登録日2017-11-08
公開日2018-01-17
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
5SVA
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BU of 5sva by Molmil
Mediator-RNA Polymerase II Pre-Initiation Complex
分子名称: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ...
著者Robinson, P.J, Bushnell, D.A, Kornberg, R.D.
登録日2016-08-05
公開日2016-09-28
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (15.3 Å)
主引用文献Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
3QT1
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BU of 3qt1 by Molmil
RNA polymerase II variant containing A Chimeric RPB9-C11 subunit
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P.
登録日2011-02-22
公開日2011-03-23
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Evolution of two modes of intrinsic RNA polymerase transcript cleavage.
J.Biol.Chem., 286, 2011
5U5Q
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BU of 5u5q by Molmil
12 Subunit RNA Polymerase II at Room Temperature collected using SFX
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A.
登録日2016-12-07
公開日2017-03-29
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep, 7, 2017
5U0S
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BU of 5u0s by Molmil
Cryo-EM structure of the Mediator-RNAPII complex
分子名称: Mediator complex subunit 10, Mediator complex subunit 11, Mediator complex subunit 14, ...
著者Tsai, K.-L, Yu, X, Gopalan, S, Chao, T.-C, Zhang, Y, Florens, L, Washburn, M.P, Murakami, K, Conaway, R.C, Conaway, J.W, Asturias, F.
登録日2016-11-26
公開日2017-03-08
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
8JH2
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BU of 8jh2 by Molmil
RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
分子名称: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
著者Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
登録日2023-05-22
公開日2023-11-29
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH4
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RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
著者Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
登録日2023-05-22
公開日2023-11-29
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
著者Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
登録日2023-05-22
公開日2023-11-29
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JCH
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BU of 8jch by Molmil
Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol II Rat1-PTTC1)
分子名称: 5'-3' exoribonuclease 2, DNA (38-MER), DNA-directed RNA polymerase II subunit RPB1, ...
著者Zeng, Y, Zhang, Y.
登録日2023-05-11
公開日2024-01-31
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of exoribonuclease-mediated mRNA transcription termination.
Nature, 628, 2024
6O85
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BU of 6o85 by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Nguyen, H.C, Kenner, L.R, Frost, A.S.
登録日2019-03-08
公開日2019-05-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O81
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Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to translation initiation factor 2 from Homo sapiens
分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Nguyen, H, Kenner, L, Frost, A.
登録日2019-03-08
公開日2019-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O9Z
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BU of 6o9z by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ...
著者Nguyen, H.C, Kenner, L.R, Frost, A.S.
登録日2019-03-15
公開日2019-05-15
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
登録日2019-03-14
公開日2019-05-29
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
7QP7
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BU of 7qp7 by Molmil
Structure of the human 48S initiation complex in closed state (h48S AUG closed)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
登録日2022-01-03
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7QP6
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Structure of the human 48S initiation complex in open state (h48S AUG open)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
登録日2022-01-03
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7SYS
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BU of 7sys by Molmil
Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII).
分子名称: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYR
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BU of 7syr by Molmil
Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt).
分子名称: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
1NT9
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Complete 12-subunit RNA polymerase II
分子名称: DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ...
著者Armache, K.-J, Kettenberger, H, Cramer, P.
登録日2003-01-29
公開日2003-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Architecture of initiation-competent 12-subunit RNA polymerase II
Proc.Natl.Acad.Sci.USA, 100, 2003

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