Mediator-RNA Polymerase II Pre-Initiation Complex

Summary for 5SVA

EMDB information8305 8307 8308
DescriptorDNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... (42 entities in total)
Functional Keywordstranscriptional initiation, mediator, pre-initiation complex, carboxy-terminal domain (ctd), transcription, transferase-dna complex, transferase/dna
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains40
Total molecular weight1522751.47
Robinson, P.J.,Bushnell, D.A.,Kornberg, R.D. (deposition date: 2016-08-05, release date: 2016-09-28, Last modification date: 2019-11-27)
Primary citation
Robinson, P.J.,Trnka, M.J.,Bushnell, D.A.,Davis, R.E.,Mattei, P.J.,Burlingame, A.L.,Kornberg, R.D.
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166:1411-1422.e16, 2016
PubMed: 27610567 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2016.08.050
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers503.2%9.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-09-16