Elongation complex of RNA polymerase II with artificial RdRP scaffold

Summary for 2R92

DescriptorRNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3'), RNA (5'-R(*CP*UP*UP*GP*AP*CP*GP*CP*CP*UP*GP*GP*UP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, ... (16 entities in total)
Functional Keywordstransferase/dna/rna, dna-binding, phosphorylation, rna polymerase ii, metal-binding, nuclear protein, transcription bubble, elongation complex, transferase, transcription, rna-dependent, rna-dependent rna synthesis, rdrp, ddrp, rna-binding, dna-directed rna polymerase, magnesium, nucleotidyltransferase, nucleus, ubl conjugation, zinc, zinc-finger, polymorphism, cytoplasm, dna damage, dna repair, mrna processing, transferase-rna complex, transferase/rna
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationNucleus P04050 P08518 P16370 P20433 P20434 P34087 P20436 P38902
Cytoplasm  P20435
Nucleus, nucleolus  P27999 P22139 P40422
Total number of polymer chains14
Total molecular weight525253.22
Lehmann, E.,Brueckner, F.,Cramer, P. (deposition date: 2007-09-12, release date: 2007-11-27, Last modification date: 2017-10-25)
Primary citation
Lehmann, E.,Brueckner, F.,Cramer, P.
Molecular basis of RNA-dependent RNA polymerase II activity.
Nature, 450:445-449, 2007
PubMed: 18004386 (PDB entries with the same primary citation)
DOI: 10.1038/nature06290
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.2475210.1%8.4%1.0%0.70MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16