8XXL
 
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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8XXM
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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8XXN
 | | Cryo-EM structure of the human 43S ribosome with PDCD4 | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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8VLB
 | | Crystal structure of EloBC-VHL-CDO1 complex bound to compound 4 molecular glue | | 分子名称: | CITRIC ACID, Cysteine dioxygenase type 1, Elongin-B, ... | | 著者 | Shu, W, Ma, X, Tutter, A, Buckley, D, Golosov, A, Michaud, G. | | 登録日 | 2024-01-11 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A small molecule VHL molecular glue degrader for cysteine dioxygenase 1
To Be Published
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8VL9
 | | Crystal structure of EloBC-VHL-CDO1 complex bound to compound 8 molecular glue | | 分子名称: | CITRIC ACID, Cysteine dioxygenase type 1, Elongin-B, ... | | 著者 | Shu, W, Ma, X, Tutter, A, Buckley, D, Golosov, A, Michaud, G. | | 登録日 | 2024-01-11 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A small molecule VHL molecular glue degrader for cysteine dioxygenase 1
To Be Published
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8XSY
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Li, X, Wang, M, Cheng, J. | | 登録日 | 2024-01-10 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8XSX
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Li, X, Wang, M, Cheng, J. | | 登録日 | 2024-01-10 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8XSZ
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Li, X, Wang, M, Cheng, J. | | 登録日 | 2024-01-10 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8RM5
 | | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'SS oligo, NHP2-like protein 1, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | 登録日 | 2024-01-05 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8XEP
 | | Crystal structure of a Legionella pneumophila type IV effector in complex with ubiquitin | | 分子名称: | SULFATE ION, Type IV effector MavL, Ubiquitin | | 著者 | Tan, J.X, Wang, X.F, Zhou, Y, Zhu, Y.Q. | | 登録日 | 2023-12-12 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Legionella effector LnaB is a phosphoryl AMPylase that impairs phosphosignalling.
Nature, 631, 2024
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8X7W
 | | Structure of dimeric human SCMC complex | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | | 著者 | Chi, P, Ou, G, Liu, S, Lu, Y, Li, J, Li, J, Wang, X, Deng, D. | | 登録日 | 2023-11-26 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Cryo-EM structure of the human subcortical maternal complex and the associated discovery of infertility-associated variants.
Nat.Struct.Mol.Biol., 2024
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8X7V
 | | Structure of human SCMC ternary complex | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | | 著者 | Chi, P, Ou, G, Liu, S, Lu, Y, Li, J.H, Li, J.L, Wang, X, Deng, D. | | 登録日 | 2023-11-26 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Cryo-EM structure of the human subcortical maternal complex and the associated discovery of infertility-associated variants.
Nat.Struct.Mol.Biol., 2024
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8X7I
 | | Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by intein-based E2-Ub-NCP conjugation strategy | | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | | 登録日 | 2023-11-24 | | 公開日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Biorxiv, 2024
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8X7J
 | | Cryo-EM structures of RNF168/UbcH5c-Ub/nucleosomes complex determined by activity-based chemical trapping strategy | | 分子名称: | DNA (144-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | | 登録日 | 2023-11-24 | | 公開日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Biorxiv, 2024
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8V28
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8V27
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8V26
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8V25
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8R57
 | | CryoEM structure of wheat 40S ribosomal subunit, head domain | | 分子名称: | 40S ribosomal protein S12, 40S ribosomal protein S15, 40S ribosomal protein S16, ... | | 著者 | Kravchenko, O.V, Baymukhametov, T.N, Afonina, Z.A, Vasilenko, K.S. | | 登録日 | 2023-11-16 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | High-Resolution Structure and Internal Mobility of a Plant 40S Ribosomal Subunit.
Int J Mol Sci, 24, 2023
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8R5H
 | | Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2 | | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 5-azanylpentan-2-one, Bromodomain-containing protein 4, ... | | 著者 | Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. | | 登録日 | 2023-11-16 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
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8UZH
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8WZN
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8WZO
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8R1F
 | | Monomeric E6AP-E6-p53 ternary complex | | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | | 著者 | Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. | | 登録日 | 2023-11-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
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8R1G
 | | Dimeric ternary structure of E6AP-E6-p53 | | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | | 著者 | Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H. | | 登録日 | 2023-11-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
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