Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8VL9

Crystal structure of EloBC-VHL-CDO1 complex bound to compound 8 molecular glue

This is a non-PDB format compatible entry.
Summary for 8VL9
Entry DOI10.2210/pdb8vl9/pdb
Descriptorvon Hippel-Lindau disease tumor suppressor, Elongin-B, Elongin-C, ... (8 entities in total)
Functional Keywordsvhl, cdo1, vhl-small molecule-cdo1 ternary complex, degradation, apoptosis
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight66504.03
Authors
Shu, W.,Ma, X.,Tutter, A.,Buckley, D.,Golosov, A.,Michaud, G. (deposition date: 2024-01-11, release date: 2024-03-13)
Primary citationTutter, A.,Buckley, D.,Golosov, A.,Ma, X.,Shu, W.,Michaud, G.
A small molecule VHL molecular glue degrader for cysteine dioxygenase 1
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon