8VLB
Crystal structure of EloBC-VHL-CDO1 complex bound to compound 4 molecular glue
Summary for 8VLB
Entry DOI | 10.2210/pdb8vlb/pdb |
Related | 8VL9 |
Descriptor | von Hippel-Lindau disease tumor suppressor, Elongin-B, Elongin-C, ... (8 entities in total) |
Functional Keywords | vhl, cdo1, vhl-small molecule-cdo1 ternary complex, degradation, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 66485.05 |
Authors | Shu, W.,Ma, X.,Tutter, A.,Buckley, D.,Golosov, A.,Michaud, G. (deposition date: 2024-01-11, release date: 2024-03-13) |
Primary citation | Tutter, A.,Buckley, D.,Golosov, A.,Ma, X.,Shu, W.,Michaud, G. A small molecule VHL molecular glue degrader for cysteine dioxygenase 1 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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