8VLB

Crystal structure of EloBC-VHL-CDO1 complex bound to compound 4 molecular glue

Summary for 8VLB

• Entry DOI: 10.2210/pdb8vlb/pdb
• Related: 8VL9
• Descriptor: von Hippel-Lindau disease tumor suppressor, Elongin-B, Elongin-C, ... (8 entities in total)
• Functional Keywords: vhl, cdo1, vhl-small molecule-cdo1 ternary complex, degradation, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 66485.05

Authors

Shu, W.,Ma, X.,Tutter, A.,Buckley, D.,Golosov, A.,Michaud, G. (deposition date: 2024-01-11, release date: 2024-03-13)

• Primary citation: Tutter, A.,Buckley, D.,Golosov, A.,Ma, X.,Shu, W.,Michaud, G.; A small molecule VHL molecular glue degrader for cysteine dioxygenase 1; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)