1QRY
 
 | | Homeobox protein VND (ventral nervous system defective protein) | | 分子名称: | PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) | | 著者 | Xiang, B. | | 登録日 | 1999-06-16 | | 公開日 | 1999-07-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation.
Biochemistry, 42, 2003
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1P7J
 | | Crystal structure of engrailed homeodomain mutant K52E | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | | 著者 | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | | 登録日 | 2003-05-02 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
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1PUF
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1P7I
 | | CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | | 著者 | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | | 登録日 | 2003-05-02 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS
J.Biol.Chem., 278, 2003
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1POG
 | | SOLUTION STRUCTURE OF THE OCT-1 POU-HOMEO DOMAIN DETERMINED BY NMR AND RESTRAINED MOLECULAR DYNAMICS | | 分子名称: | OCT-1 POU HOMEODOMAIN DNA-BINDING PROTEIN | | 著者 | Cox, M, Van Tilborg, P.J.A, De Laat, W, Boelens, R, Van Leeuwen, H.C, Van Der Vliet, P.C, Kaptein, R. | | 登録日 | 1994-10-12 | | 公開日 | 1995-07-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics.
J.Biomol.NMR, 6, 1995
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1APL
 | | CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS | | 分子名称: | DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN) | | 著者 | Wolberger, C, Vershon, A.K, Liu, B, Johnson, A.D, Pabo, C.O. | | 登録日 | 1993-10-04 | | 公開日 | 1993-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 67, 1991
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5Z2S
 | | Crystal structure of DUX4-HD2 domain | | 分子名称: | Double homeobox protein 4 | | 著者 | Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. | | 登録日 | 2018-01-03 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
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5ZFZ
 | | Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant | | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | | 登録日 | 2018-03-07 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
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5ZFW
 | | Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant | | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | | 登録日 | 2018-03-07 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
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5ZFY
 | | Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant | | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | | 登録日 | 2018-03-07 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
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5Z2T
 | | Crystal structure of DNA-bound DUX4-HD2 | | 分子名称: | 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3', Double homeobox protein 4 | | 著者 | Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G. | | 登録日 | 2018-01-04 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.623 Å) | | 主引用文献 | Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
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5Z6Z
 | | Crystal structure of human DUX4 homeodomains bound to DNA | | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4 | | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | | 登録日 | 2018-01-26 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
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1AHD
 | | DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX | | 分子名称: | DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia | | 著者 | Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | | 登録日 | 1993-04-02 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-04-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.
J.Mol.Biol., 234, 1993
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1AKH
 | | MAT A1/ALPHA2/DNA TERNARY COMPLEX | | 分子名称: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ... | | 著者 | Li, T, Jin, Y, Vershon, A.K, Wolberger, C. | | 登録日 | 1997-05-19 | | 公開日 | 1998-05-20 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
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6A8R
 | | Crystal structure of DUX4 HD2 domain associated with ERG DNA binding site | | 分子名称: | DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), Double homeobox protein 4 | | 著者 | Dong, X, Zhang, H, Cheng, N, Meng, G. | | 登録日 | 2018-07-10 | | 公開日 | 2018-10-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element.
Leukemia, 33, 2019
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1DU0
 | | ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX | | 分子名称: | DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3'), ENGRAILED HOMEODOMAIN | | 著者 | Grant, R.A, Rould, M.A, Klemm, J.D, Pabo, C.O. | | 登録日 | 2000-01-13 | | 公開日 | 2000-07-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
Biochemistry, 39, 2000
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1B72
 | | PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX | | 分子名称: | DNA (5'-D(*AP*CP*TP*CP*TP*AP*TP*GP*AP*TP*TP*GP*AP*TP*CP*GP*GP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*CP*GP*AP*TP*CP*AP*AP*TP*CP*AP*TP*AP*GP*AP*G)-3'), PROTEIN (HOMEOBOX PROTEIN HOX-B1), ... | | 著者 | Piper, D.E, Batchelor, A.H, Chang, C.-P, Cleary, M.L, Wolberger, C. | | 登録日 | 1999-01-27 | | 公開日 | 1999-02-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.
Cell(Cambridge,Mass.), 96, 1999
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1BW5
 | | THE NMR SOLUTION STRUCTURE OF THE HOMEODOMAIN OF THE RAT INSULIN GENE ENHANCER PROTEIN ISL-1, 50 STRUCTURES | | 分子名称: | INSULIN GENE ENHANCER PROTEIN ISL-1 | | 著者 | Ippel, J.H, Larsson, G, Behravan, G, Zdunek, J, Lundqvist, M, Schleucher, J, Lycksell, P.-O, Wijmenga, S.S. | | 登録日 | 1998-09-29 | | 公開日 | 1999-06-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the homeodomain of the rat insulin-gene enhancer protein isl-1. Comparison with other homeodomains.
J.Mol.Biol., 288, 1999
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1ENH
 | | STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN | | 分子名称: | ENGRAILED HOMEODOMAIN | | 著者 | Clarke, N.D, Kissinger, C.R, Desjarlais, J, Gilliland, G.L, Pabo, C.O. | | 登録日 | 1994-05-20 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural studies of the engrailed homeodomain.
Protein Sci., 3, 1994
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2HOT
 | | Phage selected homeodomain bound to modified DNA | | 分子名称: | 3-PROP-2-YN-1-YL-1,3-OXAZOLIDIN-2-ONE, 5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*CP*CP*GP*GP*A)-3', ... | | 著者 | Feldman, M.E, Simon, M.D, Shokat, K.M. | | 登録日 | 2006-07-16 | | 公開日 | 2006-12-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structure and properties of a re-engineered homeodomain protein-DNA interface.
Acs Chem.Biol., 1, 2006
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2K40
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2JWT
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2HOA
 | | STRUCTURE DETERMINATION OF THE ANTP(C39->S) HOMEODOMAIN FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION USING A NOVEL STRATEGY FOR THE STRUCTURE CALCULATION WITH THE PROGRAMS DIANA, CALIBA, HABAS AND GLOMSA | | 分子名称: | ANTENNAPEDIA PROTEIN | | 著者 | Guntert, P, Qian, Y.-Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | | 登録日 | 1992-04-04 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure determination of the Antp (C39----S) homeodomain from nuclear magnetic resonance data in solution using a novel strategy for the structure calculation with the programs DIANA, CALIBA, HABAS and GLOMSA.
J.Mol.Biol., 217, 1991
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2H1K
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2HI3
 | | Solution structure of the homeodomain-only protein HOP | | 分子名称: | Homeodomain-only protein | | 著者 | Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W. | | 登録日 | 2006-06-28 | | 公開日 | 2007-01-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Analysis of the structure and function of the transcriptional coregulator HOP
Biochemistry, 45, 2006
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