PDB: 10540 件ウェブページステータス検索Chemie searchBIRD

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3SI0	Structure of glycosylated human glutaminyl cyclase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutaminyl-peptide cyclotransferase, ... 著者 Parthier, C, Carrillo, D, Stubbs, M.T. 登録日 2011-06-17 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center. Biochemistry, 50, 2011
5UVK	Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation 分子名称: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN 著者 Martin-Garcia, J.M, Conrad, C.E, Nelson, G, Stander, N, Zatsepin, N.A, Zook, J, Zhu, L, Geiger, J, Chun, E, Kissick, D, Hilgart, M.C, Ogata, C, Ishchenko, A, Nagaratnam, N, Roy-Chowdhury, S, Coe, J, Subramanian, G, Schaffer, A, James, D, Ketawala, G, Venugopalan, N, Xu, S, Corcoran, S, Ferguson, D, Weierstall, U, Spence, J.C.H, Cherezov, V, Fromme, P, Fischetti, R.F, Liu, W. 登録日 2017-02-20 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. Iucrj, 4, 2017
5UXZ	X-ray crystal structure of Halotag bound to the P9 benzothiadiazole fluorogenic ligand 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Haloalkane dehalogenase, ... 著者 Dunham, N.P, Boal, A.K. 登録日 2017-02-23 公開日 2017-03-08 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification. Biochemistry, 56, 2017
5UQ1	Crystal structure of human Cdk2-Spy1 complex 分子名称: Cyclin-dependent kinase 2, Speedy protein A 著者 McGrath, D.A, Tripathi, S.M, Rubin, S.M. 登録日 2017-02-06 公開日 2017-07-05 最終更新日 2017-08-09 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins. EMBO J., 36, 2017
3TJH	42F3-p3A1/H2-Ld complex 分子名称: 42F3 alpha, 42F3 beta, H2-Ld SBM2, ... 著者 Adams, J.J, Kruse, A, Kranz, D.M, Garcia, K.C. 登録日 2011-08-24 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity, 35, 2011
2BLV	Trypsin before a high dose x-ray "burn" 分子名称: BENZAMIDINE, CALCIUM ION, GLYCEROL, ... 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-08 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
2BG9	REFINED STRUCTURE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR AT 4A RESOLUTION. 分子名称: ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN, BETA CHAIN, ... 著者 Unwin, N. 登録日 2004-12-17 公開日 2005-02-16 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Refined Structure of the Nicotinic Acetylcholine Receptor at 4A Resolution J.Mol.Biol., 346, 2005
3RKZ	Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model. 分子名称: (5R,6S)-3-(L-alanyl)-5,6,15,15,18-pentamethyl-17-oxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-12,8-(metheno)[1,5,9]triazacyclotetradecino[1,2-a]indole-9-carboxamide, Heat shock protein HSP 90-alpha 著者 Zapf, C.W, Bloom, J.D, Li, Z, Dushin, R.G, Nittoli, T, Otteng, M, Nikitenko, A, Golas, J.M, Liu, H, Lucas, J, Boschelli, F, Vogan, E, Olland, A, Johnson, M, Levin, J.I. 登録日 2011-04-18 公開日 2011-07-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5693 Å) 主引用文献 Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model. Bioorg.Med.Chem.Lett., 21, 2011
5U0E	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-benzyl-2-sulfanylidene-1,3-thiazolidin-4-one, 1,2-ETHANEDIOL, Carbonic anhydrase 2, ... 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-23 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
5UVL	Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation 分子名称: CALCIUM ION, NITRATE ION, Proteinase K 著者 Martin-Garcia, J.M, Conrad, C.E, Nelson, G, Stander, N, Zatsepin, N.A, Zook, J, Zhu, L, Geiger, J, Chun, E, Kissick, D, Hilgart, M.C, Ogata, C, Ishchenko, A, Nagaratnam, N, Roy-Chowdhury, S, Coe, J, Subramanian, G, Schaffer, A, James, D, Ketawala, G, Venugopalan, N, Xu, S, Corcoran, S, Ferguson, D, Weierstall, U, Spence, J.C.H, Cherezov, V, Fromme, P, Fischetti, R.F, Liu, W. 登録日 2017-02-20 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCrJ, 4, 2017
3SE9	Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 分子名称: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kwong, P.D, Zhou, T. 登録日 2011-06-10 公開日 2011-08-10 最終更新日 2021-04-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
5T7D	Crystal structure of Streptomyces hygroscopicus bialaphos resistance (BAR) protein in complex with acetyl coenzyme A 分子名称: ACETATE ION, ACETYL COENZYME *A, Phosphinothricin N-acetyltransferase 著者 Christ, B, Weng, J.K. 登録日 2016-09-04 公開日 2017-06-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Non-specific activities of the major herbicide-resistance gene BAR. Nat Plants, 3, 2017
5T7E	Crystal structure of Streptomyces hygroscopicus Bialaphos Resistance (BAR) protein in complex with Coenzyme A and L-phosphinothricin 分子名称: COENZYME A, PHOSPHINOTHRICIN, Phosphinothricin N-acetyltransferase, ... 著者 Christ, B, Weng, J.K. 登録日 2016-09-04 公開日 2017-06-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Non-specific activities of the major herbicide-resistance gene BAR. Nat Plants, 3, 2017
3SX9	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-132 分子名称: 3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Larson, E.T, Merritt, E.A. 登録日 2011-07-14 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1. J.Med.Chem., 55, 2012
5U0D	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-(2,4-dimethoxyphenyl)-2-sulfanylidene-1,3-oxazolidin-4-one, Carbonic anhydrase 2, GLYCEROL, ... 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-23 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
3REE	Crystal structure of mitoNEET 分子名称: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER 著者 Funk, M.O, Arif, W, Xu, S, Mueser, T.C. 登録日 2011-04-04 公開日 2011-04-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Complexes of the Outer Mitochondrial Membrane Protein MitoNEET with Resveratrol-3-Sulfate. Biochemistry, 50, 2011
5VGY	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5S)-5-[(2,4-dimethoxyphenyl)methyl]-5-hydroxy-2-sulfanylideneimidazolidin-4-one, Carbonic anhydrase 2, SODIUM ION, ... 著者 Peat, T.S. 登録日 2017-04-11 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
2ES0	Structure of the regulator of G-protein signaling domain of RGS6 分子名称: regulator of G-protein signalling 6 著者 Schoch, G.A, Phillips, C, Turnbull, A, Niesen, F, Johansson, C, Elkins, J.M, Longman, E, Gilealdi, C, Sobott, F, Ball, L, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) 登録日 2005-10-25 公開日 2005-11-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
2CCE	Parallel Configuration of pLI E20S 分子名称: General control protein GCN4 著者 Yadav, M.K, Leman, L.J, Price, D.J, Brooks 3rd, C.L, Stout, C.D, Ghadiri, M.R. 登録日 2006-01-16 公開日 2006-04-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution. Biochemistry, 45, 2006
5VL4	Accidental minimum contact crystal lattice formed by a redesigned protein oligomer 分子名称: T33-53H-B 著者 Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T. 登録日 2017-04-24 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering. Protein Sci., 29, 2020
3T3Z	Human Cytochrome P450 2E1 in complex with pilocarpine 分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Meneely, K.M, DeVore, N.M, Scott, E.E. 登録日 2011-07-25 公開日 2011-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
5VFD	Diazabicyclooctenone ETX2514 bound to Class D beta lactamase OXA-24 from A. baumannii 分子名称: (2S,5R)-1-formyl-4-methyl-5-[(sulfooxy)amino]-1,2,5,6-tetrahydropyridine-2-carboxamide, (2S,5R)-4-methyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]oct-3-ene-2-carboxamide, Beta-lactamase, ... 著者 Olivier, N.B, Lahiri, S. 登録日 2017-04-07 公開日 2017-06-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 ETX2514 is a broad-spectrum beta-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol, 2, 2017
2EWM	Crystal Structure of the (S)-Specific 1-Phenylethanol Dehydrogenase of the Denitrifying Bacterium Strain EbN1 分子名称: (S)-1-Phenylethanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Hoeffken, H.W. 登録日 2005-11-04 公開日 2006-03-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure and Enzyme kinetics of the (S)-Specific 1-Phenylethanol Dehydrogenase of the denitrifying bacterium Strain EbN1 Biochemistry, 45, 2006
5W19	Tryptophan indole-lyase complex with oxindolyl-L-alanine 分子名称: 1-carboxy-1-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]azaniumyl}-2-[(3R)-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-ide, POTASSIUM ION, Tryptophanase 著者 Phillips, R.S, Wood, Z.A. 登録日 2017-06-02 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism. Acta Crystallogr D Struct Biol, 74, 2018
2F5W	Cross-linked barnase soaked in 3 M thiourea 分子名称: Ribonuclease, THIOUREA, ZINC ION 著者 Prange, T, Salem, M. 登録日 2005-11-28 公開日 2006-04-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations. Biochim.Biophys.Acta, 1764, 2006

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