5W19
Tryptophan indole-lyase complex with oxindolyl-L-alanine
Summary for 5W19
Entry DOI | 10.2210/pdb5w19/pdb |
Descriptor | Tryptophanase, POTASSIUM ION, 1-carboxy-1-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]azaniumyl}-2-[(3R)-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-ide, ... (4 entities in total) |
Functional Keywords | pyridoxal-5'-phosphate, aminotransferase fold, tryptophan metabolism, inhibition, lyase |
Biological source | Proteus vulgaris |
Total number of polymer chains | 4 |
Total formula weight | 212189.73 |
Authors | Phillips, R.S.,Wood, Z.A. (deposition date: 2017-06-02, release date: 2018-06-06, Last modification date: 2023-10-04) |
Primary citation | Phillips, R.S.,Buisman, A.A.,Choi, S.,Hussaini, A.,Wood, Z.A. The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism. Acta Crystallogr D Struct Biol, 74:748-759, 2018 Cited by PubMed: 30082510DOI: 10.1107/S2059798318003352 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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