3T3Z

Human Cytochrome P450 2E1 in complex with pilocarpine

Summary for 3T3Z

• Entry DOI: 10.2210/pdb3t3z/pdb
• Related: 3E4E 3E6I 3GPH 3KOH 3LC4 3T3Q 3T3R 3T3S
• Related PRD ID: PRD_900003
• Descriptor: Cytochrome P450 2E1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• Functional Keywords: cyp2e1, cytochrome p450 2e1, p450 2e1, heme protein, monooxygenase, drug metabolism, xenobiotic metabolism, endoplasmic reticulum, membrane, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 224902.12

Authors

Meneely, K.M.,DeVore, N.M.,Scott, E.E. (deposition date: 2011-07-25, release date: 2011-12-07, Last modification date: 2023-11-29)

• Primary citation: DeVore, N.M.,Meneely, K.M.,Bart, A.G.,Stephens, E.S.,Battaile, K.P.,Scott, E.E.; Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine.; Febs J., 279:1621-1631, 2012; PubMed: 22051186; DOI: 10.1111/j.1742-4658.2011.08412.x

Experimental method

X-RAY DIFFRACTION (2.35 Å)