2ES0

Structure of the regulator of G-protein signaling domain of RGS6

Summary for 2ES0

Entry DOI	10.2210/pdb2es0/pdb
Descriptor	regulator of G-protein signalling 6 (2 entities in total)
Functional Keywords	human rgs6, regulator of g-protein signaling 6, gtpase-activating proteins (gap), domain swap, structural genomics, structural genomics consortium, sgc, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P49758
Total number of polymer chains	1
Total formula weight	17236.52
Authors	Schoch, G.A.,Phillips, C.,Turnbull, A.,Niesen, F.,Johansson, C.,Elkins, J.M.,Longman, E.,Gilealdi, C.,Sobott, F.,Ball, L.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,von Delft, F.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2005-10-25, release date: 2005-11-29, Last modification date: 2023-08-23)
Primary citation	Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P. Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008 Cited by PubMed: 18434541 DOI: 10.1073/pnas.0801508105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation