1G47
 
 | | 1ST LIM DOMAIN OF PINCH PROTEIN | | 分子名称: | PINCH PROTEIN, ZINC ION | | 著者 | Velyvis, A, Yang, Y, Wu, C, Qin, J. | | 登録日 | 2000-10-26 | | 公開日 | 2001-02-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain.
J.Biol.Chem., 276, 2001
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3MTG
 | | Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative adenosylhomocysteinase 2 | | 著者 | Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-04-30 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
TO BE PUBLISHED
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6HMY
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8BOO
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3MVJ
 | | Human cyclic AMP-dependent protein kinase PKA inhibitor complex | | 分子名称: | (3R)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | | 著者 | Pandit, J, Vajdos, F. | | 登録日 | 2010-05-04 | | 公開日 | 2010-06-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Design of selective, ATP-competitive inhibitors of Akt.
J.Med.Chem., 53, 2010
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3MUK
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1GGL
 | | HUMAN CELLULAR RETINOL BINDING PROTEIN III | | 分子名称: | PROTEIN (CELLULAR RETINOL-BINDING PROTEIN III) | | 著者 | Calderone, V, Zanotti, G, Folli, C, Ottonello, S, Bolchi, A, Stoppini, M, Berni, R. | | 登録日 | 2000-08-23 | | 公開日 | 2001-03-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1GG5
 | | CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION | | 分子名称: | 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | | 著者 | Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M. | | 登録日 | 2000-07-12 | | 公開日 | 2001-09-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones.
Structure, 9, 2001
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8DNT
 | | SARS-CoV-2 specific T cell receptor | | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ... | | 著者 | Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P. | | 登録日 | 2022-07-11 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Nat Commun, 14, 2023
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3MTN
 | | Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor | | 分子名称: | CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ... | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-04-30 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
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8DSX
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1FYJ
 | | SOLUTION STRUCTURE OF MULTI-FUNCTIONAL PEPTIDE MOTIF-1 PRESENT IN HUMAN GLUTAMYL-PROLYL TRNA SYNTHETASE (EPRS). | | 分子名称: | MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE | | 著者 | Jeong, E.-J, Hwang, G.-S, Kim, K.H, Kim, M.J, Kim, S, Kim, K.-S. | | 登録日 | 2000-10-02 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of multifunctional peptide motifs in human bifunctional tRNA synthetase: identification of RNA-binding residues and functional implications for tandem repeats.
Biochemistry, 39, 2000
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1G4Y
 | | 1.60 A CRYSTAL STRUCTURE OF THE GATING DOMAIN FROM SMALL CONDUCTANCE POTASSIUM CHANNEL COMPLEXED WITH CALCIUM-CALMODULIN | | 分子名称: | CALCIUM ION, CALCIUM-ACTIVATED POTASSIUM CHANNEL RSK2, CALMODULIN, ... | | 著者 | Schumacher, M.A, Rivard, A, Bachinger, H.P, Adelman, J.P. | | 登録日 | 2001-01-07 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Nature, 410, 2001
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6HGI
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3BBP
 | | Rab6-GTP:GCC185 Rab binding domain complex | | 分子名称: | GRIP and coiled-coil domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Schweizer Burguete, A, Fenn, T.D, Brunger, A.T, Pfeffer, S.R. | | 登録日 | 2007-11-09 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.
Cell(Cambridge,Mass.), 132, 2008
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6NE1
 | | Designed repeat protein in complex with Fz4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Pfs, ... | | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | | 登録日 | 2018-12-15 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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6NE4
 | | Designed repeat protein specifically in complex with Fz7CRD | | 分子名称: | 1,2-ETHANEDIOL, Designed repeat binding protein, Frizzled-7, ... | | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | | 登録日 | 2018-12-16 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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4R2Q
 | | Wilms Tumor Protein (WT1) zinc fingers in complex with formylated DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5FC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | | 登録日 | 2014-08-12 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Genes Dev., 28, 2014
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6HNI
 | | The ligand-bound, closed structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile. | | 分子名称: | 1,2-ETHANEDIOL, ABC-type transport system, sugar-family extracellular solute-binding protein, ... | | 著者 | Bradshaw, W.J, Kovacs-Simon, A, Harmer, N.J, Michell, S.L, Acharya, K.R. | | 登録日 | 2018-09-15 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile.
J.Biol.Chem., 294, 2019
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1GH6
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4RH7
 | | Crystal structure of human cytoplasmic dynein 2 motor domain in complex with ADP.Vi | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ... | | 著者 | Schmidt, H, Zalyte, R, Urnavicius, L, Carter, A.P. | | 登録日 | 2014-10-01 | | 公開日 | 2014-12-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Structure of human cytoplasmic dynein-2 primed for its power stroke.
Nature, 518, 2015
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1FZG
 | | CRYSTAL STRUCTURE OF FRAGMENT D FROM HUMAN FIBRINOGEN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN | | 著者 | Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F. | | 登録日 | 1999-01-01 | | 公開日 | 1999-06-08 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
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6NFY
 | | Crystal structure of nonphosphorylated, HPK1 kinase domain in complex with sunitinib in the inactive state. | | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | | 登録日 | 2018-12-21 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
J.Biol.Chem., 294, 2019
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4ROU
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1GEN
 | | C-TERMINAL DOMAIN OF GELATINASE A | | 分子名称: | CALCIUM ION, CHLORIDE ION, GELATINASE A, ... | | 著者 | Libson, A.M, Gittis, A.G, Collier, I.E, Marmer, B.L, Goldberg, G.G, Lattman, E.E. | | 登録日 | 1995-07-19 | | 公開日 | 1996-08-17 | | 最終更新日 | 2018-03-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of the haemopexin-like C-terminal domain of gelatinase A.
Nat.Struct.Biol., 2, 1995
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