6HNI

The ligand-bound, closed structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile.

Summary for 6HNI

Entry DOI	10.2210/pdb6hni/pdb
Descriptor	ABC-type transport system, sugar-family extracellular solute-binding protein, TYROSINE, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	substrate binding protein, adhesin, tyrosine binding protein, lipoprotein, transport protein
Biological source	Peptoclostridium difficile 630 (Clostridium difficile)
Total number of polymer chains	1
Total formula weight	34440.87
Authors	Bradshaw, W.J.,Kovacs-Simon, A.,Harmer, N.J.,Michell, S.L.,Acharya, K.R. (deposition date: 2018-09-15, release date: 2019-08-28, Last modification date: 2024-01-24)
Primary citation	Bradshaw, W.J.,Bruxelle, J.F.,Kovacs-Simon, A.,Harmer, N.J.,Janoir, C.,Pechine, S.,Acharya, K.R.,Michell, S.L. Molecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile. J.Biol.Chem., 294:15850-15861, 2019 Cited by PubMed: 31420448 DOI: 10.1074/jbc.RA119.010120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation