6NE1

Designed repeat protein in complex with Fz4

Summary for 6NE1

• Entry DOI: 10.2210/pdb6ne1/pdb
• Related: 6NDZ
• Descriptor: Frizzled-4, Pfs, NACHT and Ankyrin domain protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: frizzled, designed protein, biosynthetic protein, biosynthetic protein-signaling protein complex, biosynthetic protein/signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 34010.18

Authors

Miao, Y.,Jude, K.M.,Garcia, K.C. (deposition date: 2018-12-15, release date: 2019-05-15, Last modification date: 2023-10-11)

• Primary citation: Dang, L.T.,Miao, Y.,Ha, A.,Yuki, K.,Park, K.,Janda, C.Y.,Jude, K.M.,Mohan, K.,Ha, N.,Vallon, M.,Yuan, J.,Vilches-Moure, J.G.,Kuo, C.J.,Garcia, K.C.,Baker, D.; Receptor subtype discrimination using extensive shape complementary designed interfaces.; Nat.Struct.Mol.Biol., 26:407-414, 2019; PubMed: 31086346; DOI: 10.1038/s41594-019-0224-z

Experimental method

X-RAY DIFFRACTION (3.011 Å)