PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

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7ADR	CO bound as bridging ligand at the active site of vanadium nitrogenase VFe protein 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ... 著者 Rohde, M, Grunau, K, Einsle, O. 登録日 2020-09-16 公開日 2020-09-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 CO Binding to the FeV Cofactor of CO-Reducing Vanadium Nitrogenase at Atomic Resolution. Angew.Chem.Int.Ed.Engl., 59, 2020
5XE0	Crystal structure of EV-D68-3Dpol in complex with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein 著者 Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C. 登録日 2017-03-30 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol J. Virol., 91, 2017
4LVC	Crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine 分子名称: ACETATE ION, ADENOSINE, AMMONIUM ION, ... 著者 Manszewski, T, Singh, K, Imiolczyk, B, Jaskolski, M. 登録日 2013-07-26 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii. Acta Crystallogr.,Sect.D, 71, 2015
6AJI	Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with Rimonabant 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ... 著者 Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. 登録日 2018-08-27 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
6AJF	Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Drug exporters of the RND superfamily-like protein,Endolysin, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside 著者 Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. 登録日 2018-08-27 公開日 2018-12-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.698 Å) 主引用文献 Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
6ZMS	Coxsackievirus B4 strain E2 分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... 著者 Flatt, J.W, Domanska, A, Butcher, S.J. 登録日 2020-07-03 公開日 2021-03-17 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses. Commun Biol, 4, 2021
6AJG	Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, DODECYL-BETA-D-MALTOSIDE, Drug exporters of the RND superfamily-like protein,Endolysin, ... 著者 Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. 登録日 2018-08-27 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.604 Å) 主引用文献 Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
6UVS	Human Connexin-26 (Low pH open conformation) 分子名称: Gap junction beta-2 protein 著者 Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M. 登録日 2019-11-04 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels. Cell Rep, 31, 2020
6AJJ	Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ... 著者 Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. 登録日 2018-08-27 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.794 Å) 主引用文献 Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
4LXI	Crystal Structure of the S105A mutant of a carbon-carbon bond hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with 5,8-diF HOPDA 分子名称: (3E,5R)-5-fluoro-6-(2-fluorophenyl)-2,6-dioxohex-3-enoic acid, MCP Hydrolase, SODIUM ION 著者 Bhowmik, S, Bolin, J.T. 登録日 2013-07-29 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 A substrate-assisted mechanism of nucleophile activation in a ser-his-asp containing C-C bond hydrolase. Biochemistry, 52, 2013
6UUZ	Structure of ACLY in the presence of citrate and CoA 分子名称: ATP-citrate synthase, COENZYME A 著者 Xuepeng, W, Ronen, M. 登録日 2019-11-01 公開日 2020-01-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6V67	Apo Structure of the De Novo PD-1 Binding Miniprotein GR918.2 分子名称: PD-1 Binding Miniprotein GR918.2 著者 Bick, M.J, Bryan, C.M, Baker, D, Dimaio, F, Kang, A. 登録日 2019-12-04 公開日 2020-12-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Computational design of a synthetic PD-1 agonist. Proc.Natl.Acad.Sci.USA, 118, 2021
5XVU	Crystal structure of the protein kinase CK2 catalytic domain from Plasmodium falciparum bound to ATP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 El Sahili, A, Lescar, J, Ruiz-Carrillo, D, Lin, J.Q. 登録日 2017-06-28 公開日 2017-07-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition. Sci Rep, 8, 2018
4MLE	Human Glucokinase in Complex with Novel Amino Thiazole Activator 分子名称: 3-(benzyloxy)-N-(4-methyl-1,3-thiazol-2-yl)pyridin-2-amine, Glucokinase, alpha-D-glucopyranose 著者 Voegtli, W.C. 登録日 2013-09-06 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification of a New Class of Glucokinase Activators through Structure-Based Design. J.Med.Chem., 56, 2013
6BDJ	Crystal structure of dioxygenase Tetur07g02040 分子名称: FE (III) ION, Tetur07g02040 著者 Daneshian, L, Schlachter, C.R, Chruszcz, M. 登録日 2017-10-23 公開日 2018-11-14 最終更新日 2019-05-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional characterization of an intradiol ring-cleavage dioxygenase from the polyphagous spider mite herbivore Tetranychus urticae Koch. Insect Biochem.Mol.Biol., 107, 2019
4MPN	Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS10 分子名称: 2-[(2,4-dihydroxyphenyl)sulfonyl]-2,3-dihydro-1H-isoindole-4,6-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... 著者 Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. 登録日 2013-09-13 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket. J.Biol.Chem., 289, 2014
4MLH	Human Glucokinase in Complex with a Novel Amino Thiazole Allosteric Activator 分子名称: 3-(benzyloxy)-5-methyl-N-(4-methyl-1,3-thiazol-2-yl)pyridin-2-amine, Glucokinase, alpha-D-glucopyranose 著者 Voegtli, W.C. 登録日 2013-09-06 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of a New Class of Glucokinase Activators through Structure-Based Design. J.Med.Chem., 56, 2013
6V3K	Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ419 (compound 4c) 分子名称: 4-azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-(5-oxidanylpentyl)-1,8-naphthyridine-3-carboxamide, Chimeric Sso7d and HIV-1 integrase, MAGNESIUM ION, ... 著者 Lyumkis, D, Jozwik, I.K, Passos, D. 登録日 2019-11-25 公開日 2020-02-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science, 367, 2020
7AZP	Structure of the human mitochondrial HSPD1 single ring 分子名称: 60 kDa heat shock protein, mitochondrial 著者 Klebl, D.P, Feasey, M.C, Muench, S.P. 登録日 2020-11-17 公開日 2021-02-10 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structure of human mitochondrial HSPD1. Iscience, 24, 2021
5Y3E	Crystal structure of SARS coronavirus papain-like protease in complex with glycerol 分子名称: GLYCEROL, Replicase polyprotein 1a, SODIUM ION, ... 著者 Lin, M.H, Chou, C.Y. 登録日 2017-07-28 公開日 2018-01-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes Antiviral Res., 150, 2017
4LA3	Crystal structure of dimethylsulphoniopropionate (DMSP) lyase DddQ Y131A in complex with DMSP 分子名称: 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, Dimethylsulphoniopropionate (DMSP) lyase DddQ, ZINC ION 著者 Zhang, Y, Li, C. 登録日 2013-06-19 公開日 2014-01-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Molecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide Proc.Natl.Acad.Sci.USA, 111, 2014
7AI4	Crystal structure of the KLC1-TPR domain truncated from its nonTPR region ([A1-B6]-Delta-nonTPR fragment) 分子名称: Isoform C of Kinesin light chain 1,Isoform C of Kinesin light chain 1 著者 Menetrey, J, Llinas, P. 登録日 2020-09-26 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.795 Å) 主引用文献 Structural investigations of the dynamics of the TPR domain of kinesin light chain To Be Published
7AIE	Crystal structure of a truncated form of the KLC1-TPR domain ([A1-B5] fragment) - Monoclinic crystal form 分子名称: Kinesin light chain 1, MAGNESIUM ION 著者 Menetrey, J, Llinas, P. 登録日 2020-09-27 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.287 Å) 主引用文献 Structural investigations of the dynamics of the TPR domain of kinesin light chain To Be Published
6UV5	Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate 分子名称: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION 著者 Wei, X, Marmorstein, R. 登録日 2019-11-01 公開日 2019-12-25 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
5Y4K	Crystal structure of DddY mutant Y260A 分子名称: ACRYLIC ACID, DMSP lyase DddY, ZINC ION 著者 Zhang, Y.Z, Li, C.Y. 登録日 2017-08-03 公開日 2017-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanistic Insights into Dimethylsulfoniopropionate Lyase DddY, a New Member of the Cupin Superfamily. J. Mol. Biol., 429, 2017

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