6V67

Apo Structure of the De Novo PD-1 Binding Miniprotein GR918.2

Summary for 6V67

• Entry DOI: 10.2210/pdb6v67/pdb
• Descriptor: PD-1 Binding Miniprotein GR918.2 (2 entities in total)
• Functional Keywords: pd-1, disulfide miniprotein, computational design, binder, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 9879.20

Authors

Bick, M.J.,Bryan, C.M.,Baker, D.,Dimaio, F.,Kang, A. (deposition date: 2019-12-04, release date: 2020-12-09, Last modification date: 2024-04-03)

• Primary citation: Bryan, C.M.,Rocklin, G.J.,Bick, M.J.,Ford, A.,Majri-Morrison, S.,Kroll, A.V.,Miller, C.J.,Carter, L.,Goreshnik, I.,Kang, A.,DiMaio, F.,Tarbell, K.V.,Baker, D.; Computational design of a synthetic PD-1 agonist.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34272285; DOI: 10.1073/pnas.2102164118

Experimental method

X-RAY DIFFRACTION (1.07 Å)