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4WFN
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BU of 4wfn by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
登録日2014-09-16
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
2IWA
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BU of 2iwa by Molmil
Unbound glutaminyl cyclotransferase from Carica papaya.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLUTAMINE CYCLOTRANSFERASE, ...
著者Guevara, T, Mallorqui-Fernandez, N, Garcia-Castellanos, R, Petersen, G.E, Lauritzen, C, Pedersen, J, Arnau, J, Gomis-Ruth, F.X, Sola, M.
登録日2006-06-27
公開日2006-07-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Papaya Glutamine Cyclotransferase Shows a Singular Five-Fold Beta-Propeller Architecture that Suggests a Novel Reaction Mechanism.
Biol.Chem., 387, 2006
4CON
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BU of 4con by Molmil
Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with citrate in the active site
分子名称: ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, CITRIC ACID
著者Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T.
登録日2014-01-29
公開日2015-01-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
7NTN
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BU of 7ntn by Molmil
The structure of RRM domain of human TRMT2A at 2 A resolution
分子名称: CHLORIDE ION, SODIUM ION, SULFATE ION, ...
著者Davydova, E, Janowski, R, Witzenberger, M, Niessing, D.
登録日2021-03-10
公開日2022-01-19
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.016 Å)
主引用文献Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death.
Comput Struct Biotechnol J, 20, 2022
4COM
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BU of 4com by Molmil
Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with MES in the active site
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, PENTAETHYLENE GLYCOL, ...
著者Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T.
登録日2014-01-29
公開日2015-01-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
4COL
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BU of 4col by Molmil
Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with dATP bound in the specificity site
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, MAGNESIUM ION, ...
著者Aurelius, O, Johansson, R, Bagenholm, V, Beck, T, Balhuizen, A, Lundin, D, Sjoberg, B.M, Mulliez, E, Logan, D.T.
登録日2014-01-29
公開日2015-05-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
4D1W
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BU of 4d1w by Molmil
A H224Y mutant for VIM-7 from Pseudomonas aeruginosa
分子名称: METALLO-B-LACTAMASE, ZINC ION
著者Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O.
登録日2014-05-05
公開日2014-06-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
6YX5
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BU of 6yx5 by Molmil
Structure of DrrA from Legionella pneumophilia in complex with human Rab8a
分子名称: MAGNESIUM ION, Multifunctional virulence effector protein DrrA, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Schneider, S, Du, J, von Wrisberg, M.K, Lang, K, Itzen, A.
登録日2020-04-30
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1.
Nat Commun, 12, 2021
6ZJ3
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BU of 6zj3 by Molmil
Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis
分子名称: 18S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Matzov, D, Halfon, H, Zimmerman, E, Rozenberg, H, Bashan, A, Gray, M.W, Yonath, A.E, Shalev-Benami, M.
登録日2020-06-27
公開日2020-10-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis.
Nucleic Acids Res., 48, 2020
4D1U
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BU of 4d1u by Molmil
A D120A mutant of VIM-7 from Pseudomonas aeruginosa
分子名称: METALLO-B-LACTAMASE, ZINC ION
著者Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O.
登録日2014-05-05
公開日2014-06-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
4D1T
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BU of 4d1t by Molmil
High resolution structure of native tVIM-7 from Pseudomonas aeruginosa
分子名称: METALLO-B-LACTAMASE, ZINC ION
著者Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O.
登録日2014-05-05
公開日2014-06-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
4D1V
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BU of 4d1v by Molmil
A F218Y mutant of VIM-7 from Pseudomonas aeruginosa
分子名称: METALLO-B-LACTAMASE, ZINC ION
著者Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O.
登録日2014-05-05
公開日2014-06-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
4DO7
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BU of 4do7 by Molmil
Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group c2
分子名称: Amidohydrolase 2, SULFATE ION, ZINC ION
著者Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Seidel, R.D, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Al Obaidi, N.F, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-02-09
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group c2
to be published
7Y0I
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BU of 7y0i by Molmil
Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
分子名称: ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, Histone-lysine N-methyltransferase ASH1L, ZINC ION
著者Yu, M, Zeng, L.
登録日2022-06-05
公開日2022-10-12
実験手法SOLUTION NMR
主引用文献Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.
Front Oncol, 12, 2022
7XFG
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BU of 7xfg by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
分子名称: Histone acetyltransferase p300, NUT family member 1, ZINC ION
著者Yu, D, Zeng, L, Zhou, M.-M.
登録日2022-04-01
公開日2023-04-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7XEZ
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BU of 7xez by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2
分子名称: Histone acetyltransferase p300,NUT family member 1, ZINC ION
著者Yu, D, Zeng, L, Zhou, M.-M.
登録日2022-03-31
公開日2023-04-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7XIN
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BU of 7xin by Molmil
Crystal structure of DODC from Pseudomonas
分子名称: DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE
著者Li, X, Zhou, Y.L, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Sun, D.Y, Zeng, Z.X.
登録日2022-04-13
公開日2023-04-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of DODC from Pseudomonas
To Be Published
7XIO
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BU of 7xio by Molmil
Crystal structure of TYR from Ralstonia
分子名称: PHOSPHATE ION, Polyphenol oxidase
著者Sun, D.Y, Cui, P.P, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Zhang, J, Li, X, Zeng, Z.X.
登録日2022-04-13
公開日2023-04-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of TYR from Ralstonia
To Be Published
8XRP
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BU of 8xrp by Molmil
The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 receptor subunit beta-2, ...
著者Chen, H.Q, Wang, X.Q, Ge, X.F, Zeng, J.W, Wang, J.W.
登録日2024-01-07
公開日2024-07-24
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structure and assembly of the human IL-12 signaling complex.
Structure, 2024
1YBI
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BU of 1ybi by Molmil
Crystal structure of HA33A, a neurotoxin-associated protein from Clostridium botulinum type A
分子名称: non-toxin haemagglutinin HA34
著者Arndt, J.W, Gu, J, Jaroszewski, L, Schwarzenbacher, R, Hanson, M, Lebeda, F.J, Stevens, R.C.
登録日2004-12-20
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Structure of the Neurotoxin-associated Protein HA33/A from Clostridium botulinum Suggests a Reoccurring beta-Trefoil Fold in the Progenitor Toxin Complex.
J.Mol.Biol., 346, 2005
6D9M
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BU of 6d9m by Molmil
T4-Lysozyme fusion to Geobacter GGDEF
分子名称: ACETATE ION, Fusion protein of Endolysin,Response receiver sensor diguanylate cyclase, GAF domain-containing, ...
著者Hallberg, Z, Doxzen, K, Kranzusch, P.J, Hammond, M.
登録日2018-04-30
公開日2019-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration.
Elife, 8, 2019
1YIO
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BU of 1yio by Molmil
Crystallographic structure of response regulator StyR from Pseudomonas fluorescens
分子名称: MAGNESIUM ION, MERCURY (II) ION, response regulatory protein
著者Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M.
登録日2005-01-12
公開日2005-09-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism
STRUCTURE, 13, 2005
6D6U
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BU of 6d6u by Molmil
Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and flumazenil, conformation A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, GAMMA-AMINO-BUTANOIC ACID, ...
著者Zhu, S, Noviello, C.M, Teng, J, Walsh Jr, R.M, Kim, J.J, Hibbs, R.E.
登録日2018-04-22
公開日2018-06-27
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structure of a human synaptic GABAAreceptor.
Nature, 559, 2018
1Y69
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BU of 1y69 by Molmil
RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans
分子名称: 23S ribosomal RNA, 50S ribosomal protein L16, 50S ribosomal protein L27, ...
著者Wilson, D.N, Schluenzen, F, Harms, J.M, Yoshida, T, Ohkubo, T, Albrecht, R, Buerger, J, Kobayashi, Y, Fucini, P.
登録日2004-12-04
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
6D6T
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BU of 6d6t by Molmil
Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and flumazenil, conformation B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, GAMMA-AMINO-BUTANOIC ACID, ...
著者Zhu, S, Noviello, C.M, Teng, J, Walsh Jr, R.M, Kim, J.J, Hibbs, R.E.
登録日2018-04-22
公開日2018-06-27
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structure of a human synaptic GABAAreceptor.
Nature, 559, 2018

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