7Y0I
Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
Summary for 7Y0I
Entry DOI | 10.2210/pdb7y0i/pdb |
Descriptor | Histone-lysine N-methyltransferase ASH1L, ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, ZINC ION (3 entities in total) |
Functional Keywords | ash1l, phd domain, h3k4me2, prostate cancer, structural protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 8170.11 |
Authors | |
Primary citation | Yu, M.,Jia, Y.,Ma, Z.,Ji, D.,Wang, C.,Liang, Y.,Zhang, Q.,Yi, H.,Zeng, L. Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer. Front Oncol, 12:906807-906807, 2022 Cited by PubMed: 36033518DOI: 10.3389/fonc.2022.906807 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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