7Y0I
Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone-lysine N-methyltransferase ASH1L | polymer | 56 | 6446.4 | 1 | UniProt (Q9NR48) Pfam (PF20826) In PDB | Homo sapiens | ASH1-like protein,huASH1,Absent small and homeotic disks protein 1 homolog,Lysine N-methyltransferase 2H |
| 2 | B | ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA | polymer | 15 | 1592.8 | 1 | UniProt (by SIFTS) (Q6NXT2) In PDB | Homo sapiens | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 5 - 56 (UniProt: Q9NR48)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Thr 39 | Ser 2618 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 8039.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 8170.1 |
