1SBI
 
 | | SUBTILISIN BPN' 8397 (E.C. 3.4.21.14) MUTANT (M50F, N76D, G169A, Q206C, N218S) | | 分子名称: | CALCIUM ION, SUBTILISIN 8397 | | 著者 | Kidd, R.D, Yennawar, H.P, Farber, G.K. | | 登録日 | 1995-09-01 | | 公開日 | 1995-12-07 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A weak calcium binding site in subtilisin BPN' has a dramatic effect on protein stability.
J.Am.Chem.Soc., 118, 1996
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4EMN
 | | Crystal structure of RpfB catalytic domain in complex with benzamidine | | 分子名称: | BENZAMIDINE, Probable resuscitation-promoting factor rpfB, SULFATE ION | | 著者 | Ruggiero, A, Marchant, J, Squeglia, F, Makarov, V, De Simone, A, Berisio, R. | | 登録日 | 2012-04-12 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis.
J.Biomol.Struct.Dyn., 31, 2013
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1SUB
 | | CALCIUM-INDEPENDENT SUBTILISIN BY DESIGN | | 分子名称: | ACETONE, CALCIUM ION, POTASSIUM ION, ... | | 著者 | Gallagher, T, Bryan, P, Gilliland, G.L. | | 登録日 | 1992-06-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Calcium-independent subtilisin by design.
Proteins, 16, 1993
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6CMH
 | | SYNTHETIC LINEAR MODIFIED ENDOTHELIN-1 AGONIST | | 分子名称: | PROTEIN (ENDOTHELIN-1) | | 著者 | Hewage, C.M, Jiang, L, Parkinson, J.A, Ramage, R, Sadler, I.H. | | 登録日 | 1998-09-03 | | 公開日 | 1999-09-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling.
J.Pept.Res., 53, 1999
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5XJY
 | | Cryo-EM structure of human ABCA1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette sub-family A member 1, ... | | 著者 | Qian, H.W, Yan, N, Gong, X. | | 登録日 | 2017-05-04 | | 公開日 | 2017-06-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of the Human Lipid Exporter ABCA1.
Cell, 169, 2017
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3GST
 | | STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE | | 分子名称: | (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION | | 著者 | Ji, X, Ammon, H.L, Armstrong, R.N, Gilliland, G.L. | | 登録日 | 1993-06-07 | | 公開日 | 1993-10-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.
Biochemistry, 33, 1994
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3WJM
 | | Crystal structure of Bombyx mori Sp2/Sp3 heterohexamer | | 分子名称: | Arylphorin, Silkworm storage protein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yuan, Y.A, Hou, Y. | | 登録日 | 2013-10-11 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of Bombyx mori arylphorins reveals a 3:3 heterohexamer with multiple papain cleavage sites
Protein Sci., 23, 2014
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8UTG
 | | An RNA G-Quadruplex from the NS5 gene in the West Nile Virus Genome | | 分子名称: | AMMONIUM ION, POTASSIUM ION, RNA (5'-R(*UP*AP*UP*GP*GP*AP*AP*GP*AP*GP*GP*CP*GP*GP*UP*UP*GP*GP*UP*AP*U)-3') | | 著者 | Terrell, J.R, Le, T.T, Wilson, W.D, Siemer, J.L. | | 登録日 | 2023-10-31 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structure of an RNA G-quadruplex from the West Nile virus genome.
Nat Commun, 15, 2024
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1D7Y
 | | CRYSTAL STRUCTURE OF NADH-DEPENDENT FERREDOXIN REDUCTASE, BPHA4 | | 分子名称: | FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Senda, T, Yamada, T, Sakurai, N, Kubota, M, Nishizaki, T, Masai, E, Fukuda, M, Mitsui, Y. | | 登録日 | 1999-10-21 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of NADH-dependent ferredoxin reductase component in biphenyl dioxygenase.
J.Mol.Biol., 304, 2000
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5MWG
 | | Crystal structure of the human BRPF1 bromodomain in complex with BZ091 | | 分子名称: | NITRATE ION, Peregrin, ~{N}-[1,4-dimethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide | | 著者 | Zhu, J, Caflisch, A. | | 登録日 | 2017-01-18 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
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6CBD
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1TGM
 | | Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution | | 分子名称: | 2-(ACETYLOXY)BENZOIC ACID, CALCIUM ION, Phospholipase A2, ... | | 著者 | Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P. | | 登録日 | 2004-05-28 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structure of a complex formed between group II phospholipase A2 and aspirin at 1.86 A resolution
To be Published
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1TJK
 | | Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe- Leu- Ser- Thr- Lys at 1.2 A resolution | | 分子名称: | Phospholipase A2, SULFATE ION, synthetic peptide | | 著者 | Singh, N, Jabeen, T, Somvanshi, R.K, Sharma, S, Perbandt, M, Dey, S, Betzel, C, Singh, T.P. | | 登録日 | 2004-06-06 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe - Leu - Ser - Thr - Lys at 1.2 A resolution
To be Published
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1SUE
 | | SUBTILISIN BPN' FROM BACILLUS AMYLOLIQUEFACIENS, MUTANT | | 分子名称: | DIISOPROPYL PHOSPHONATE, SODIUM ION, SUBTILISIN BPN' | | 著者 | Gallagher, D.T, Bryan, P, Pan, Q, Gilliland, G.L. | | 登録日 | 1998-02-17 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanism of ionic strength dependence of crystal growth rates in a subtilisin variant.
J.Cryst.Growth, 193, 1998
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1ST2
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1D48
 | | STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA (MAGNESIUM FREE) AT 1 ANGSTROM RESOLUTION | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE | | 著者 | Egli, M, Williams, L.D, Gao, Q, Rich, A. | | 登録日 | 1991-09-11 | | 公開日 | 1992-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution.
Biochemistry, 30, 1991
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3GUR
 | | Crystal Structure of mu class glutathione S-transferase (GSTM2-2) in complex with glutathione and 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) | | 分子名称: | 1,2-ETHANEDIOL, GLUTATHIONE, Glutathione S-transferase Mu 2, ... | | 著者 | Federici, L, Lo Sterzo, C, Di Matteo, A, Scaloni, F, Federici, G, Caccuri, A.M. | | 登録日 | 2009-03-30 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases
Cancer Res., 69, 2009
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4YU9
 | | Crystal Structure of double mutant Y115E Y117E human Glutaminyl Cyclase | | 分子名称: | 1,2-ETHANEDIOL, Glutaminyl-peptide cyclotransferase, SULFATE ION, ... | | 著者 | Di Pisa, F, Pozzi, C, Benvenuti, M, Mangani, S. | | 登録日 | 2015-03-18 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease.
Acta Crystallogr.,Sect.F, 71, 2015
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1OAP
 | | Mad structure of the periplasmique domain of the Escherichia coli PAL protein | | 分子名称: | PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, SULFATE ION | | 著者 | Abergel, C, Walburger, A, Bouveret, E, Claverie, J.M. | | 登録日 | 2003-01-20 | | 公開日 | 2004-02-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystallization and preliminary crystallographic study of the peptidoglycan-associated lipoprotein from Escherichia coli.
Acta Crystallogr.,Sect.D, 57, 2001
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4EM7
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3H4K
 | | Crystal structure of the wild type Thioredoxin glutatione reductase from Schistosoma mansoni in complex with auranofin | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GOLD ION, ... | | 著者 | Angelucci, F, Dimastrogiovanni, D, Miele, A.E, Boumis, G, Brunori, M, Bellelli, A. | | 登録日 | 2009-04-20 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.
J.Biol.Chem., 284, 2009
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1DD7
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1U3T
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1UBN
 | | SELENOSUBTILISIN BPN | | 分子名称: | CALCIUM ION, PROTEIN (SELENOSUBTILISIN BPN) | | 著者 | McRee, D.E, McTigue, M, Hilvert, D. | | 登録日 | 1999-06-02 | | 公開日 | 1999-06-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins.
Biochemistry, 38, 1999
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1TW7
 | | Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target | | 分子名称: | SODIUM ION, protease | | 著者 | Martin, P, Vickrey, J.F, Proteasa, G, Jimenez, Y.L, Wawrzak, Z, Winters, M.A, Merigan, T.C, Kovari, L.C. | | 登録日 | 2004-06-30 | | 公開日 | 2005-07-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target
Structure, 13, 2005
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