Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1TW7

Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target

Summary for 1TW7
Entry DOI10.2210/pdb1tw7/pdb
Related1RPI 1RQ9 1RV7
Descriptorprotease, SODIUM ION (3 entities in total)
Functional Keywordshiv protease, aids, polyprotein, hydrolase, aspartyl protease, multi-drug resistance
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains2
Total formula weight21525.20
Authors
Martin, P.,Vickrey, J.F.,Proteasa, G.,Jimenez, Y.L.,Wawrzak, Z.,Winters, M.A.,Merigan, T.C.,Kovari, L.C. (deposition date: 2004-06-30, release date: 2005-07-19, Last modification date: 2023-08-23)
Primary citationMartin, P.,Vickrey, J.F.,Proteasa, G.,Jimenez, Y.L.,Wawrzak, Z.,Winters, M.A.,Merigan, T.C.,Kovari, L.C.
Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target
Structure, 13:1887-1895, 2005
Cited by
PubMed: 16338417
DOI: 10.1016/j.str.2005.11.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon