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6O2N
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CDTb Double Heptamer Short Form Modeled from Cryo-EM Map Reconstructed using C7 Symmetry
分子名称: ADP-ribosyltransferase binding component
著者Lacy, D.B, Sheedlo, M.J, Anderson, D.M.
登録日2019-02-24
公開日2019-10-30
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore.
Nat Microbiol, 5, 2020
5HYI
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BU of 5hyi by Molmil
Glycosylated, disulfide-linked Hole-Hole Fc fragment
分子名称: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Kuglstatter, A, Stihle, M, Benz, J.
登録日2016-02-01
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products.
Protein Eng. Des. Sel., 30, 2017
7UWL
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Structure of the IL-25-IL-17RB-IL-17RA ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWM
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Structure of the IL-17A-IL-17RA binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWK
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Structure of the higher-order IL-25-IL-17RB complex
分子名称: Interleukin-17 receptor B, Interleukin-25
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7UWJ
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Structure of the homodimeric IL-25-IL-17RB binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor B, Interleukin-25
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
6NWW
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Crystal structure of the RRM domain of S. pombe Puf1 in the P212121 space group
分子名称: CHLORIDE ION, Pumilio domain-containing protein C56F2.08c
著者Qiu, C, Hall, T.M.T.
登録日2019-02-07
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity.
Nucleic Acids Res., 47, 2019
6C63
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Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin
分子名称: 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, POTASSIUM ION, RNA (32-MER), ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-01-17
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.900028 Å)
主引用文献Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness.
Biochemistry, 57, 2018
5XP0
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BU of 5xp0 by Molmil
Crystal structure of master biofilm regulator CsgD regulatory domain
分子名称: MAGNESIUM ION, Probable csgAB operon transcriptional regulatory protein
著者Wen, Y, Ouyang, Z.
登録日2017-05-31
公開日2018-06-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of master biofilm regulator CsgD regulatory domain reveals an atypical receiver domain.
Protein Sci., 26, 2017
7UWN
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BU of 7uwn by Molmil
Structure of the IL-17A-IL-17RA-IL-17RC ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ...
著者Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C.
登録日2022-05-03
公開日2022-07-27
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Organizing structural principles of the IL-17 ligand-receptor axis.
Nature, 609, 2022
7DMU
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BU of 7dmu by Molmil
Structure of SARS-CoV-2 spike receptor-binding domain complexed with high affinity ACE2 mutant 3N39
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Arimori, T, Takagi, J.
登録日2020-12-07
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Nat Commun, 12, 2021
8JMR
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BU of 8jmr by Molmil
Crystal structure of hinokiresinol synthase in complex with 1,7-bis(4-hydroxyphenyl)hepta-1,6-dien-3-one
分子名称: 1,7-bis(4-hydroxyphenyl)hepta-1,6-dien-3-one, Hinokiresinol synthase alpha subunit, Hinokiresinol synthase beta subunit, ...
著者Ding, Y, Ushimaru, R, Mori, T, Abe, I.
登録日2023-06-05
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Mechanistic Insights into the C-C Bond-Forming Rearrangement Reaction Catalyzed by Heterodimeric Hinokiresinol Synthase.
J.Am.Chem.Soc., 145, 2023
8JMQ
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Crystal structure of hinokiresinol synthase
分子名称: Hinokiresinol synthase alpha subunit, Hinokiresinol synthase beta subunit
著者Ding, Y, Ushimaru, R, Mori, T, Abe, I.
登録日2023-06-05
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Mechanistic Insights into the C-C Bond-Forming Rearrangement Reaction Catalyzed by Heterodimeric Hinokiresinol Synthase.
J.Am.Chem.Soc., 145, 2023
6CQ6
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BU of 6cq6 by Molmil
K2P2.1(TREK-1) apo structure
分子名称: CADMIUM ION, DECANE, POTASSIUM ION, ...
著者Lolicato, M, Minor, D.L.
登録日2018-03-14
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
2B00
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BU of 2b00 by Molmil
Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycocholate
分子名称: CALCIUM ION, GLYCOCHOLIC ACID, Phospholipase A2, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B04
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BU of 2b04 by Molmil
Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycochenodeoxycholate
分子名称: CALCIUM ION, CHLORIDE ION, GLYCOCHENODEOXYCHOLIC ACID, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
7CY1
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BU of 7cy1 by Molmil
Crystal Structure of MglC from Myxococcus xanthus
分子名称: Mutual gliding motility protein C, SODIUM ION
著者Thakur, K.G, Kapoor, S, Kodesia, A.
登録日2020-09-03
公開日2021-01-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural characterization of Myxococcus xanthus MglC, a component of the polarity control system, and its interactions with its paralog MglB.
J.Biol.Chem., 2021
5LSB
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BU of 5lsb by Molmil
Crystal structure of yeast Hsh49p in complex with Cus1p binding domain.
分子名称: Cold sensitive U2 snRNA suppressor 1, Protein HSH49
著者van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K.
登録日2016-08-24
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
6NG0
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BU of 6ng0 by Molmil
Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with sunitinib in the inactive state.
分子名称: Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide
著者Johnson, E, McTigue, M, Cronin, C.N.
登録日2018-12-21
公開日2019-05-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
J.Biol.Chem., 294, 2019
6CQ9
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BU of 6cq9 by Molmil
K2P2.1(TREK-1):ML402 complex
分子名称: CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ...
著者Lolicato, M, Minor, D.L.
登録日2018-03-14
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
8J54
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BU of 8j54 by Molmil
Crystal structure of RXR/DR2 complex
分子名称: DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ...
著者Chen, Y, Jiang, L.
登録日2023-04-21
公開日2024-01-17
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma.
Structure, 32, 2024
5JW9
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The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide
分子名称: AF4/FMR2 family member 4, RNA polymerase II elongation factor ELL2
著者Qi, S, Hurley, J.H.
登録日2016-05-11
公開日2017-02-08
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription.
Nat Commun, 8, 2017
5JZ7
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BU of 5jz7 by Molmil
NGF IN COMPLEX WITH MEDI578 scFv
分子名称: Beta-nerve growth factor, MEDI578 scFv, heavy chain, ...
著者Olsson, L.-L, Aagaard, A.
登録日2016-05-16
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
6ZIQ
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bovine ATP synthase stator domain, state 1
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Spikes, T.E, Montgomery, M.G, Walker, J.E.
登録日2020-06-26
公開日2020-09-09
最終更新日2020-09-30
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Structure of the dimeric ATP synthase from bovine mitochondria.
Proc.Natl.Acad.Sci.USA, 117, 2020
6TNG
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BU of 6tng by Molmil
Structure of FANCD2 in complex with FANCI
分子名称: Fanconi anemia complementation group I, Uncharacterized protein
著者Alcon, P, Shakeel, S, Passmore, L.A.
登録日2019-12-07
公開日2020-02-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020

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