PDB: 10619 件ウェブページステータス検索Chemie searchBIRD

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5Z6S	Crystal structure of the PPARgamma-LBD complexed with compound DS-6930 分子名称: 3-[[6-(3,5-dimethylpyridin-2-yl)oxy-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... 著者 Matsui, Y, Hanzawa, H. 登録日 2018-01-25 公開日 2018-10-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of DS-6930, a potent selective PPAR gamma modulator. Part II: Lead optimization. Bioorg. Med. Chem., 26, 2018
6ER6	Crystal structure of a computationally designed colicin endonuclease and immunity pair colEdes7/Imdes7 分子名称: Endonuclease colEdes7, immunity Imdes7 著者 Netzer, R, Listov, D, Dym, O, Albeck, S, Knop, O, Fleishman, S.J. 登録日 2017-10-17 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Ultrahigh specificity in a network of computationally designed protein-interaction pairs. Nat Commun, 9, 2018
3LZP	Crystal Structure Analysis of the 'as-isolated' P19 protein from Campylobacter jejuni at 1.65 A at pH 9.0 分子名称: COPPER (II) ION, P19 protein, SULFATE ION 著者 Doukov, T.I, Chan, A.C.K, Scofield, M, Ramin, A.B, Tom-Yew, S.A.L, Murphy, M.E.P. 登録日 2010-03-01 公開日 2010-07-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni. J.Mol.Biol., 401, 2010
2Q9O	Near-atomic resolution structure of a Melanocarpus albomyces laccase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Hakulinen, N, Rouvinen, J. 登録日 2007-06-13 公開日 2008-03-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 A near atomic resolution structure of a Melanocarpus albomyces laccase. J.Struct.Biol., 162, 2008
3CAB	Crystal structure of a pheromone binding protein from Apis mellifera soaked at pH 7.0 分子名称: GLYCEROL, Pheromone-binding protein ASP1 著者 Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. 登録日 2008-02-19 公開日 2008-06-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of the honey bee PBP pheromone and pH-induced conformational change J.Mol.Biol., 380, 2008
3PBE	Crystal structure of the mutant W207F of human secretory glutaminyl cyclase 分子名称: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION 著者 Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. 登録日 2010-10-20 公開日 2011-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
3PDC	Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor 分子名称: Epoxide hydrolase 2, N-(5-chloro-1,3-benzoxazol-2-yl)-2-cyclopentylacetamide 著者 Kurumbail, R.G, Williams, J.M. 登録日 2010-10-22 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening. J.Med.Chem., 54, 2011
5HGN	Hexameric HIV-1 CA, apo form 分子名称: Capsid protein P24 著者 Jacques, D.A, Price, A.J, James, D.A. 登録日 2016-01-08 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
5HGL	Hexameric HIV-1 CA, open conformation 分子名称: CHLORIDE ION, Capsid protein P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE 著者 Price, A.J, Jacques, D.A, James, L.C. 登録日 2016-01-08 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
6GKM	CryoEM structure of the MDA5-dsRNA filament in complex with ATP (10 mM) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... 著者 Yu, Q, Qu, K, Modis, Y. 登録日 2018-05-21 公開日 2018-11-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
2ODE	Crystal structure of the heterodimeric complex of human RGS8 and activated Gi alpha 3 分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, MAGNESIUM ION, ... 著者 Gileadi, C, Soundararajan, M, Turnbull, A.P, Elkins, J.M, Papagrigoriou, E, Pike, A.C.W, Bunkoczi, G, Gorrec, F, Umeano, C, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C.H, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) 登録日 2006-12-22 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
3GUG	Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid 分子名称: 3,5-dichloro-2-hydroxybenzoic acid, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Dhagat, U, El-Kabbani, O. 登録日 2009-03-30 公開日 2010-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid To be Published
5HQ8	Co-crystal Structure of human SMYD3 with a MEKK2 peptide at 2.13A 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ... 著者 Elkins, P.A, Bonnette, W.G. 登録日 2016-01-21 公開日 2016-03-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets. Structure, 24, 2016
1JO3	Gramicidin B in Sodium Dodecyl Sulfate Micelles (NMR) 分子名称: GRAMICIDIN B 著者 Townsley, L.E, Tucker, W.A, Hinton, J.F. 登録日 2001-07-26 公開日 2001-08-08 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structures of Gramicidins A, B, and C Incorporated Into Sodium Dodecyl Sulfate Micelles. Biochemistry, 40, 2001
1JP9	Sperm Whale met-Myoglobin (low temperature; high pressure) 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, myoglobin 著者 Urayama, P, Gruner, S.M, Phillips Jr, G.N. 登録日 2001-08-01 公開日 2002-01-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Probing substates in sperm whale myoglobin using high-pressure crystallography. Structure, 10, 2002
3Q1J	Crystal structure of tudor domain 1 of human PHD finger protein 20 分子名称: PHD finger protein 20, UNKNOWN ATOM OR ION 著者 Tempel, W, Li, Z, Wernimont, A.K, Chao, X, Bian, C, Lam, R, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2010-12-17 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins. Febs Lett., 586, 2012
4RQV	Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS2 分子名称: 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... 著者 Rettenmaier, T.J, Wells, J.A. 登録日 2014-11-05 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proc.Natl.Acad.Sci.USA, 111, 2014
3PK2	Artificial Transfer Hydrogenases for the Enantioselective Reduction of Cyclic Imines 分子名称: IRIDIUM (III) ION, Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III) 著者 Schirmer, T, Heinisch, T. 登録日 2010-11-11 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Artificial transfer hydrogenases for the enantioselective reduction of cyclic imines. Angew.Chem.Int.Ed.Engl., 50, 2011
3D14	Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea 分子名称: 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea, serine/threonine kinase 6 著者 Elling, R.A, Baskaran, S, Allen, D.A, Oslob, J.D, Romanowski, M.J. 登録日 2008-05-04 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a potent and selective aurora kinase inhibitor. Bioorg.Med.Chem.Lett., 18, 2008
4RQK	Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS1 分子名称: 3-phosphoinositide-dependent protein kinase 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Rettenmaier, T.J, Wells, J.A. 登録日 2014-11-03 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proc.Natl.Acad.Sci.USA, 111, 2014
3PSX	Crystal structure of the KT2 mutant of cytochrome P450 BM3 分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Yang, W, Whitehouse, C.J.C, Yorke, J.A, Bell, S.G, Zhou, W, Bartlam, M, Wong, L.L, Rao, Z. 登録日 2010-12-02 公開日 2011-12-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant Dalton Trans, 40, 2011
2PSO	Human StarD13 (DLC2) lipid transfer and protein localization domain 分子名称: StAR-related lipid transfer protein 13 著者 Lehtio, L, Busam, R, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Ogg, D, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC) 登録日 2007-05-07 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
3BAM	RESTRICTION ENDONUCLEASE BAMHI COMPLEX WITH DNA AND MANGANESE IONS (POST-REACTIVE COMPLEX) 分子名称: DNA (5'-D(*TP*AP*TP*G)-3'), DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*AP*TP*A)-3'), ... 著者 Viadiu, H, Aggarwal, A.K. 登録日 1998-08-19 公開日 1999-01-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The role of metals in catalysis by the restriction endonuclease BamHI. Nat.Struct.Biol., 5, 1998
3Q3F	Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase 分子名称: Ribonuclease/Ubiquitin chimeric protein, SULFATE ION 著者 Ha, J.-H, Karchin, J.M, Walker-Kopp, N, Huang, L.-S, Berry, E.A, Loh, S.N. 登録日 2010-12-21 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.169 Å) 主引用文献 Engineering domain-swapped binding interfaces by mutually exclusive folding. J.Mol.Biol., 416, 2012
2QGB	Human transthyretin (TTR) in Apo-form 分子名称: Transthyretin 著者 Connelly, S, Wilson, I.A. 登録日 2007-06-28 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. J.Med.Chem., 51, 2008

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