3GUG

Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid

Summary for 3GUG

DescriptorAldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,5-dichloro-2-hydroxybenzoic acid, ... (5 entities in total)
Functional Keywordsaldo-keto reductase, 20 alpha hydroxysteroid dehydrogenase, akr1c1, oxidoreductase, cytoplasm, nadp, polymorphism
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q04828
Total number of polymer chains1
Total molecular weight37841.13
Authors
Dhagat, U.,El-Kabbani, O. (deposition date: 2009-03-30, release date: 2010-02-09, Last modification date: 2011-07-13)
Primary citation
Dhagat, U.,Hara, A.,El-Kabbani, O.
Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid
To be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2581102.5%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3gug
no rotation
Molmil generated image of 3gug
rotated about x axis by 90°
Molmil generated image of 3gug
rotated about y axis by 90°