PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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6I0J	Crystal structure of human carbonic anhydrase I in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor 分子名称: ACETATE ION, Carbonic anhydrase 1, GLYCEROL, ... 著者 Ferraroni, M, Supuran, C.T, Bozdag, M, Chiapponi, D. 登録日 2018-10-26 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells. Eur.J.Med.Chem., 182, 2019
8R1O	Structure of C. thermophilum RNA exosome core 分子名称: Exoribonuclease phosphorolytic domain-containing protein, Exoribonuclease-like protein, Exosome complex component MTR3, ... 著者 Lazzaretti, D, Liebau, J, Pilsl, M, Sprangers, R. 登録日 2023-11-02 公開日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex Biorxiv, 2024
4K7T	Structure of the ternary complex of bacitracin, zinc, and geranyl-pyrophosphate 分子名称: GERANYL DIPHOSPHATE, SODIUM ION, ZINC ION, ... 著者 Economou, N.J, Loll, P.J. 登録日 2013-04-17 公開日 2013-08-14 最終更新日 2013-10-16 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 High-resolution crystal structure reveals molecular details of target recognition by bacitracin. Proc.Natl.Acad.Sci.USA, 110, 2013
7COQ	Hexameric Ring Complex of Engineered V1-ATPase bound to AMP-PNP: A3(De)3_(ANP)1cat 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, V-type sodium ATPase catalytic subunit A, ... 著者 Kosugi, T, Tanabe, M, Koga, N. 登録日 2020-08-05 公開日 2021-08-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.44 Å) 主引用文献 De Novo Design of Allosteric Control into Rotary Motor V1-ATPase by Restoring Lost Function To Be Published
2V9T	Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1 分子名称: ROUNDABOUT HOMOLOG 1, SLIT HOMOLOG 2 PROTEIN N-PRODUCT 著者 Morlot, C, Cusack, S, McCarthy, A.A. 登録日 2007-08-25 公開日 2007-09-25 最終更新日 2012-08-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Insights Into the Slit-Robo Complex. Proc.Natl.Acad.Sci.USA, 104, 2007
8DT4	X-ray structure of human acetylcholinesterase ternary complex with paraoxon and oxime MMB4 (POX-hAChE-MMB4) 分子名称: 1,1'-methylenebis{4-[(E)-(hydroxyimino)methyl]pyridin-1-ium}, Acetylcholinesterase, DIETHYL PHOSPHONATE, ... 著者 Kovalevsky, A.Y, Gerlits, O, Radic, Z. 登録日 2022-07-25 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering. Structure, 30, 2022
2H9E	Crystal Structure of FXa/selectide/NAPC2 ternary complex 分子名称: ACETATE ION, Anti-coagulant protein C2, Coagulation factor X heavy chain, ... 著者 Murakami, M.T, Geiger, G, Tulinsky, A, Arni, R.K. 登録日 2006-06-09 公開日 2007-02-13 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Intermolecular Interactions and Characterization of the Novel Factor Xa Exosite Involved in Macromolecular Recognition and Inhibition: Crystal Structure of Human Gla-domainless Factor Xa Complexed with the Anticoagulant Protein NAPc2 from the Hematophagous Nematode Ancylostoma caninum. J.Mol.Biol., 366, 2007
4E3S	RB69 DNA Polymerase Ternary Complex with dQTP Opposite dT 分子名称: 3-{2-deoxy-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-7-methyl-3H-imidazo[4,5-b]pyridine, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-03-10 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry, 51, 2012
8DT5	X-ray structure of human acetylcholinesterase ternary complex with paraoxon and oxime RS170B (POX-hAChE-RS170B) 分子名称: 4-carbamoyl-1-(3-{2-[(E)-(hydroxyimino)methyl]-1H-imidazol-1-yl}propyl)pyridin-1-ium, Acetylcholinesterase, DIETHYL PHOSPHONATE, ... 著者 Kovalevsky, A.Y, Gerlits, O, Radic, Z. 登録日 2022-07-25 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering. Structure, 30, 2022
1RTZ	CRYSTAL STRUCTURE OF E.COLI APO-HPPK(V83G/DEL84-89) AT 1.33 ANGSTROM RESOLUTION 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION, GLYCEROL, ... 著者 Blaszczyk, J, Ji, X. 登録日 2003-12-10 公開日 2004-02-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase. Biochemistry, 43, 2004
8DYN	Antimicrobial lasso peptide cloacaenodin 分子名称: Cloacaenodin 著者 Carson, D.V, Link, A.J. 登録日 2022-08-04 公開日 2022-12-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against Enterobacter . Acs Infect Dis., 9, 2023
7XAM	Mycobacterium smegmatis 50S ribosomal subunit from Stationary phase of growth 分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... 著者 Sengupta, J, Baid, P. 登録日 2022-03-18 公開日 2023-05-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM captures a unique conformational rearrangement in 23S rRNA helices of the Mycobacterium 50S subunit. Int.J.Biol.Macromol., 253, 2023
3VEQ	A binary complex betwwen bovine pancreatic trypsin and a engineered mutant trypsin inhibitor 分子名称: CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3 著者 Sen, U, Majumder, S, Khamrui, S, Dasgupta, J. 登録日 2012-01-09 公開日 2012-10-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824, 2012
1O9Y	Crystal structure of the C-terminal domain of the HrcQb protein from Pseudomonas syringae pv. phaseolicola 分子名称: HRCQ2 著者 Fadouloglou, V.E, Kokkinidis, M. 登録日 2002-12-20 公開日 2003-12-04 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure of Hrcqb-C, a Conserved Component of the Bacterial Type III Secretion Systems. Proc.Natl.Acad.Sci.USA, 101, 2004
7DKH	Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex 分子名称: Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ... 著者 Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F. 登録日 2020-11-24 公開日 2021-11-24 最終更新日 2022-01-05 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of the Core Module of the Yeast Paf1 Complex. J.Mol.Biol., 434, 2021
8VLQ	Structure of PmHMGR bound to mevalonate, CoA and NAD 5 minutes after reaction initiation at pH 9 分子名称: (R)-MEVALONATE, (R)-mevaldehyde, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... 著者 Purohit, V, Steussy, C.N, Stauffacher, C.V. 登録日 2024-01-12 公開日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography. Biophys.J., 123, 2024
8DSF	Structure of cIAP1 with BCCov 分子名称: (4S)-4-[2-(2-{4-[(2E)-4-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}-4-oxobut-2-en-1-yl]piperazin-1-yl}ethoxy)acetamido]-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-L-prolinamide unbound form, Baculoviral IAP repeat-containing protein 2, ZINC ION 著者 Schiemer, J.S, Calabrese, M.F. 登録日 2022-07-22 公開日 2023-03-08 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A covalent BTK ternary complex compatible with targeted protein degradation. Nat Commun, 14, 2023
2V9Q	First and second Ig domains from human Robo1 分子名称: MERCURY (II) ION, ROUNDABOUT HOMOLOG 1 著者 Morlot, C, Cusack, S, McCarthy, A.A. 登録日 2007-08-25 公開日 2007-09-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Insights Into the Slit-Robo Complex. Proc.Natl.Acad.Sci.USA, 104, 2007
5JHG	Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11 分子名称: GLYCEROL, Rho guanine nucleotide exchange factor 11, Transforming protein RhoA 著者 Wang, R, Chen, Q, Zhang, H, Yan, Z, Li, J, Miao, L, Wang, F. 登録日 2016-04-21 公開日 2017-04-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11 To Be Published
1TMJ	Crystal structure of E.coli apo-HPPK(W89A) at 1.45 Angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION, MAGNESIUM ION 著者 Blaszczyk, J, Ji, X. 登録日 2004-06-10 公開日 2005-06-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies. Biochemistry, 44, 2005
4UBE	CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE 分子名称: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Adenosine kinase 著者 Reddy, M.C.M, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Watson, M.D, Sacchettini, J.C. 登録日 2014-08-12 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.933 Å) 主引用文献 CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE TO BE PUBLISHED
8LDH	REFINED CRYSTAL STRUCTURE OF DOGFISH M4 APO-LACTATE DEHYDROGENASE 分子名称: CITRIC ACID, M4 APO-LACTATE DEHYDROGENASE 著者 Abad-Zapatero, C, Rossmann, M.G. 登録日 1988-01-04 公開日 1989-07-12 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Refined crystal structure of dogfish M4 apo-lactate dehydrogenase. J.Mol.Biol., 198, 1987
6U0M	Structure of the S. cerevisiae replicative helicase CMG in complex with a forked DNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (15-MER), ... 著者 Yuan, Z, Georgescu, R, Bai, L, Zhang, D, O'Donnell, M, Li, H. 登録日 2019-08-14 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 DNA unwinding mechanism of a eukaryotic replicative CMG helicase. Nat Commun, 11, 2020
8E2B	N-terminal domain of S. aureus GpsB 分子名称: Cell cycle protein GpsB, GLYCEROL 著者 Sacco, M, Chen, Y. 登録日 2022-08-14 公開日 2023-08-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB. Elife, 13, 2024
1NXQ	Crystal Structure of R-alcohol dehydrogenase (RADH) (apoenyzme) from Lactobacillus brevis 分子名称: MAGNESIUM ION, R-alcohol dehydrogenase 著者 Niefind, K, Muller, J, Riebel, B, Hummel, W, Schomburg, D. 登録日 2003-02-11 公開日 2003-04-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 The crystal structure of R-specific alcohol dehydrogenase from Lactobacillus brevis suggests the structural basis of its metal dependency J.Mol.Biol., 327, 2003

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