Summary for 1TMJ
| Related | 1HKA 1EQM 1EQ0 1Q0N 1EX8 1CBK 1DY3 1F9Y 1F9H 1G4C 1HQ2 1IM6 1KBR 1RU2 1RU1 1RTZ 1RB0 1TMM |
|---|---|
| Descriptor | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | pyrophosphokinase, pyrophosphoryl transfer, folate, hppk, 6-hydroxymethylpterin, 6-hydroxymethyl-7, 8-dihydropterin, antimicrobial agent, drug design, point mutant, structural mutagenesis, transferase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total molecular weight | 17935.47 |
| Authors | Blaszczyk, J.,Ji, X. (deposition date: 2004-06-10, release date: 2005-06-21, Last modification date: 2011-07-13) |
| Primary citation | Li, Y.,Blaszczyk, J.,Wu, Y.,Shi, G.,Ji, X.,Yan, H. Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies. Biochemistry, 44:8590-8599, 2005 PubMed: 15952765 (PDB entries with the same primary citation) DOI: 10.1021/bi0503495  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
