1RB0

CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI HPPK WITH 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.35 ANGSTROM RESOLUTION

Summary for 1RB0
Related1CBK 1DY3 1EQ0 1EQM 1EX8 1F9H 1F9Y 1G4C 1HKA 1HQ2 1IM6 1KBR 1Q0N 1RAO
Descriptor2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE (3 entities in total)
Functional Keywordspyrophosphokinase, pyrophosphoryl transfer, catalytic mechanism, folate, hppk, pterin, 6-hydroxymethyl-7, 8-dihydropterin, 6-hydroxymethylpterin, ternary complex, binary complex, substrate specificity, product release, antimicrobial agent, drug design, transferase
Biological sourceEscherichia coli
Total number of polymer chains1
Total formula weight18319.66
Authors
Blaszczyk, J.,Ji, X. (deposition date: 2003-10-31, release date: 2004-11-09, Last modification date: 2011-07-13)
Primary citationBlaszczyk, J.,Ji, X.,Li, Y.,Shi, G.,Yan, H.
Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Structure, 12:467-475, 2004
PubMed: 15016362
DOI: 110.1016/j.str.2004.02.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation
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PDB entries from 2021-06-16