8VLQ
Structure of PmHMGR bound to mevalonate, CoA and NAD 5 minutes after reaction initiation at pH 9
This is a non-PDB format compatible entry.
Summary for 8VLQ
Entry DOI | 10.2210/pdb8vlq/pdb |
Related | 8GDN 8SZ6 |
Descriptor | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, Mevaldyl-Coenzyme A, COENZYME A, ... (9 entities in total) |
Functional Keywords | non-rossmann fold, homodimer, reductase, hmg-coa, structural protein, oxidoreductase |
Biological source | Pseudomonas sp. 'mevalonii' |
Total number of polymer chains | 2 |
Total formula weight | 94681.91 |
Authors | |
Primary citation | Purohit, V.,Steussy, C.N.,Rosales, A.R.,Critchelow, C.J.,Schmidt, T.,Helquist, P.,Wiest, O.,Mesecar, A.,Cohen, A.E.,Stauffacher, C.V. pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography. Biophys.J., 123:622-637, 2024 Cited by PubMed: 38327055DOI: 10.1016/j.bpj.2024.02.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
Download full validation report